CAS 57375-25-4

(14E,24E)-8-bromo-5,17,19-trihydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,6,9,11-tetraoxo-1,2,6,9-tetrahydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate

Description:

The chemical substance known as "(14E,24E)-8-bromo-5,17,19-trihydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,6,9,11-tetraoxo-1,2,6,9-tetrahydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate" with the CAS number 57375-25-4 is a complex organic compound characterized by its intricate molecular structure, which includes multiple functional groups such as hydroxyl (-OH), methoxy (-OCH3), and bromo (-Br) substituents. The presence of several methyl groups contributes to its hydrophobic characteristics, while the tetraoxo and epoxide functionalities suggest potential reactivity and biological activity. This compound likely exhibits unique physical properties, such as solubility in organic solvents and potential bioactivity, making it of interest in medicinal chemistry and pharmacology. Its structural complexity may also indicate potential applications in synthetic organic chemistry or as a lead compound in drug development. However, specific data regarding its stability, reactivity, and biological effects would require further investigation through experimental studies.

Formula: C₃₇H₄₄BrNO₁₂

InChI: InChI=1/C37H44BrNO12/c1-15-11-10-12-16(2)36(47)39-27-26(38)31(44)23-24(32(27)45)30(43)20(6)34-25(23)35(46)37(8,51-34)49-14-13-22(48-9)17(3)33(50-21(7)40)19(5)29(42)18(4)28(15)41/h10-15,17-19,22,28-29,33,41-43H,1-9H3,(H,39,47)/b11-10+,14-13+,16-12+

3-Bromorifamycin S (>90%)

Controlled Product

CAS: 57375-25-4

Stability Light Sensitive, Temperature Sensitive
Applications 3-Bromorifamycin S is a derivative of Rifamycin (R508200), an antibacterial agent.
References Cellai, L., et al.: Euro. J. Med. Chem., 24, 105 (1989);

Formula: C₃₇H₄₄BrNO₁₂

Purity: >90%

Color and Shape: Neat

Molecular weight: 774.65

Ref: TR-B687090

3-Bromorifamycin S

CAS: 57375-25-4

3-Bromorifamycin S is a potent analog of rifamycin that has shown to be effective in inhibiting cancer cells. It induces apoptosis by targeting proteins involved in the cell cycle and DNA replication, leading to cell death. This compound has been studied extensively in Chinese hamster ovary cells and tumor cells, showing promising results as an anticancer agent. 3-Bromorifamycin S has also been found to be a kinase inhibitor, blocking the activity of kinases involved in cancer progression. Medicinal research on this compound has revealed its potential as a therapeutic option for various types of human cancers. Additionally, it can be detected in urine samples, making it a useful biomarker for monitoring treatment efficacy.

Formula: C₃₇H₄₄BrNO₁₂

Purity: Min. 95%

Molecular weight: 774.65 g/mol

Ref: 3D-HCA37525