CAS 57393-71-2

5,7-dihydroxy-2-(4-hydroxyphenyl)-3,6,8-trimethoxy-4H-chromen-4-one

Description:

5,7-Dihydroxy-2-(4-hydroxyphenyl)-3,6,8-trimethoxy-4H-chromen-4-one, with the CAS number 57393-71-2, is a flavonoid compound characterized by its chromone backbone, which is a fused benzopyran structure. This compound features multiple hydroxyl (-OH) groups and methoxy (-OCH3) substituents, contributing to its potential antioxidant properties. The presence of the 4-hydroxyphenyl group enhances its biological activity, making it of interest in pharmacological research. Flavonoids like this one are known for their ability to scavenge free radicals, which may provide protective effects against oxidative stress. Additionally, the specific arrangement of functional groups can influence its solubility, stability, and interaction with biological targets. This compound may also exhibit various biological activities, including anti-inflammatory and anticancer effects, although further studies are necessary to fully elucidate its mechanisms of action and therapeutic potential. Overall, 5,7-dihydroxy-2-(4-hydroxyphenyl)-3,6,8-trimethoxy-4H-chromen-4-one represents a significant area of interest in natural product chemistry and medicinal research.

Formula: C₁₈H₁₆O₈

InChI: InChI=1/C18H16O8/c1-23-16-11(20)10-12(21)17(24-2)14(8-4-6-9(19)7-5-8)26-15(10)18(25-3)13(16)22/h4-7,19-20,22H,1-3H3

SMILES: COc1c(c2c(=O)c(c(c3ccc(cc3)O)oc2c(c1O)OC)OC)O

Synonyms:

• 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-3,6,8-trimethoxy-

4',5,7-trihydroxy 3,6,8-trimethoxyflavone

CAS: 57393-71-2

Oxygen-heterocyclic compound

Formula: C₁₈H₁₆O₈

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 360.32

Ref: 5G-82675

4′,5,7-Trihydroxy-3,6,8-trimethoxyflavon

CAS: 57393-71-2

The antimicrobial activity of 4′,5,7-trihydroxy-3,6,8-trimethoxyflavon (FHT) has been demonstrated against a number of pathogenic bacteria including Staphylococcus aureus and Escherichia coli. FHT is an inhibitor of the efflux pump PmrA in staphylococci that is responsible for the resistance to quinolones. The most active flavonoids are found in flowers and include calycopterin and kaempferol.

Formula: C₁₈H₁₆O₈

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 360.3 g/mol

Ref: 3D-HCA39371