CAS 57396-72-2

3,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one

Description:

3,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one, also known by its CAS number 57396-72-2, is a flavonoid compound characterized by its complex polyphenolic structure. This substance features a benzopyran core, which is a common structural motif in flavonoids, and is substituted with hydroxyl and methoxy groups that contribute to its biological activity. The presence of multiple hydroxyl groups enhances its antioxidant properties, making it a subject of interest in pharmacological research. This compound is often studied for its potential health benefits, including anti-inflammatory, anticancer, and neuroprotective effects. Its solubility and stability can vary depending on the solvent and environmental conditions, which is important for its application in various fields, including nutraceuticals and pharmaceuticals. Additionally, the specific arrangement of functional groups influences its interaction with biological systems, making it a valuable compound for further investigation in medicinal chemistry.

Formula: C₁₆H₁₂O₆

InChI: InChI=1S/C16H12O6/c1-21-12-5-2-8(6-11(12)18)16-15(20)14(19)10-4-3-9(17)7-13(10)22-16/h2-7,17-18,20H,1H3

InChI key: InChIKey=QVYSSMFEUBQBEU-UHFFFAOYSA-N

SMILES: OC1=C(OC=2C(C1=O)=CC=C(O)C2)C3=CC(O)=C(OC)C=C3

Synonyms:

• Flavone, 3,3′,7-trihydroxy-4′-methoxy-
• 3,7,3′-Trihydroxy-4′-methoxyflavone
• 4′-Methoxyfisetin
• 3,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
• 4H-1-Benzopyran-4-one, 3,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-

4-O-Methylfisetin-d3

Controlled Product

CAS: 57396-72-2

Formula: C₁₆D₃H₉O₆

Color and Shape: Neat

Molecular weight: 303.281

Ref: TR-M295937

4-O-Methylfisetin

Controlled Product

CAS: 57396-72-2

Applications 4-O-Methylfisetin is a flavonoid that shows inhibitory effects on cAMP phosphodiesterase.
References Roengsumran, S., et. al.: J. Sci. Res. Chulalongkorn University, 25, 169 (2000)

Formula: C₁₆H₁₂O₆

Color and Shape: Neat

Molecular weight: 300.26

Ref: TR-M295935

4-o-Methylfisetin-d3

CAS: 57396-72-2

4-o-Methylfisetin-d3 is an analog of the flavonoid fisetin that has shown potent anticancer properties. It is a kinase inhibitor that targets several kinases involved in cancer cell growth and survival. Studies have shown that 4-o-Methylfisetin-d3 inhibits the activity of tolvaptan, a drug used to treat polycystic kidney disease, by blocking its binding to specific proteins. This compound induces apoptosis (programmed cell death) in human cancer cells and has been shown to inhibit tumor growth in animal models. Additionally, 4-o-Methylfisetin-d3 has been found in urine samples from Chinese individuals and may have potential as a biomarker for cancer diagnosis and treatment. Overall, this inhibitor shows promising potential for the development of new anticancer therapies.

Formula: C₁₆H₁₂O₆

Purity: Min. 95%

Molecular weight: 300.26 g/mol

Ref: 3D-HCA39672