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CAS 5741-22-0

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(±)-Moprolol

Description:
(±)-Moprolol is a beta-adrenergic antagonist, commonly known as a beta-blocker, primarily used in the treatment of hypertension and certain cardiac conditions. It is characterized by its ability to selectively block beta-1 adrenergic receptors, which are primarily located in the heart, leading to a decrease in heart rate and myocardial contractility. The compound exhibits a racemic mixture, meaning it contains equal parts of two enantiomers, which can have different pharmacological effects. Its chemical structure includes a propanolamine moiety, contributing to its activity as a beta-blocker. (±)-Moprolol is typically administered orally and is metabolized in the liver, with its pharmacokinetics influenced by factors such as age and liver function. Common side effects may include fatigue, dizziness, and gastrointestinal disturbances. As with other beta-blockers, caution is advised in patients with asthma or certain cardiovascular conditions due to potential bronchoconstriction and bradycardia. Overall, (±)-Moprolol plays a significant role in cardiovascular therapy, demonstrating the importance of beta-adrenergic modulation in clinical practice.
Formula:C13H21NO3
InChI:InChI=1/C13H21NO3/c1-10(2)14-8-11(15)9-17-13-7-5-4-6-12(13)16-3/h4-7,10-11,14-15H,8-9H2,1-3H3
InChI key:InChIKey=LFTFGCDECFPSQD-UHFFFAOYSA-N
SMILES:O(CC(CNC(C)C)O)C1=C(OC)C=CC=C1
Synonyms:
  • 1-(2-Methoxyphenoxy)-3-((1-methylethyl)amino)-2-propanol
  • 1-(2-Methoxyphenoxy)-3-(Propan-2-Ylamino)Propan-2-Ol
  • 1-(Isopropylamino)-3-(2-methoxyphenoxy)propan-2-ol
  • 1-(Isopropylamino)-3-(o-methoxyphenoxy)-2-propanol
  • 1-Isopropylamino-3-(2-methoxy-phenoxy)-propan-2-ol
  • 2-Propanol, 1-(2-methoxyphenoxy)-3-[(1-methylethyl)amino]-
  • 2-Propanol, 1-(isopropylamino)-3-(o-methoxyphenoxy)-
  • M 66527
  • Moprolol [INN]
  • Moprololum
  • See more synonyms
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