CAS 57435-86-6

Premazepam

Description:

Premazepam is a pharmaceutical compound classified as a benzodiazepine, primarily used for its anxiolytic and sedative properties. It acts on the central nervous system by enhancing the effects of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, leading to increased neuronal inhibition and a calming effect. Premazepam is known for its relatively rapid onset of action and moderate duration of effects, making it suitable for short-term management of anxiety disorders. The substance is typically administered orally and is metabolized in the liver, with its metabolites contributing to its pharmacological effects. Common side effects may include drowsiness, dizziness, and potential dependence with prolonged use. As with other benzodiazepines, caution is advised in patients with a history of substance abuse or those taking other central nervous system depressants. Due to its potential for tolerance and withdrawal symptoms, premazepam is generally prescribed for short durations and under careful medical supervision.

Formula: C₁₅H₁₅N₃O

InChI: InChI=1S/C15H15N3O/c1-10-14-12(9-18(10)2)17-13(19)8-16-15(14)11-6-4-3-5-7-11/h3-7,9H,8H2,1-2H3,(H,17,19)

InChI key: InChIKey=CNWSHOJSFGGNLC-UHFFFAOYSA-N

SMILES: CC1=C2C(=NCC(=O)NC2=CN1C)C3=CC=CC=C3

Synonyms:

• 3,7-Dihydro-6,7-dimethyl-5-phenylpyrrolo(3,4-e)(1,4)diazepin-2(1H)-one
• 6,7-dimethyl-5-phenyl-3,7-dihydropyrrolo[3,4-e][1,4]diazepin-2(1H)-one
• Brn 0617435
• Mdl 181
• Nsc 290940
• Premazepam [INN:BAN]
• Premazepamum
• Premazepamum [INN-Latin]
• Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one, 3,7-dihydro-6,7-dimethyl-5-phenyl-
• Unii-Oi7443Pdlb
• Premazepam

Premazepam

Controlled Product

CAS: 57435-86-6

Formula: C₁₅H₁₅N₃O

Color and Shape: Neat

Molecular weight: 253.299

Ref: TR-P712650

Premazepam-d3

Controlled Product

CAS: 57435-86-6

Formula: C₁₅D₃H₁₂N₃O

Color and Shape: Neat

Molecular weight: 256.318

Ref: TR-P712652

Premazepam

Controlled Product

CAS: 57435-86-6

Premazepam is an analog of the human protein kinase inhibitor, quetiapine, which has been shown to have anticancer properties. It has been found to inhibit the growth of tumor cells in Chinese hamsters and induce apoptosis in human cancer cell lines. Premazepam acts as a potent inhibitor of kinases, which are enzymes that play a critical role in regulating cell division and proliferation. This drug may be used as a potential therapeutic agent for the treatment of various types of cancer. Additionally, premazepam can be detected in urine samples and can serve as a useful biomarker for monitoring the efficacy of cancer treatments.

Formula: C₁₅H₁₅N₃O

Purity: Min. 95%

Molecular weight: 253.3 g/mol

Ref: 3D-HCA43586

Premazepam

CAS: 57435-86-6

Premazepam, a partial benzodiazepine agonist with anxiolytic and sedative effects noted in 1984, was never sold.

Formula: C₁₅H₁₅N₃O

Color and Shape: Solid

Molecular weight: 253.3

Ref: TM-T69074