CAS 5746-86-1
:(±)-Nornicotine
Description:
(±)-Nornicotine, with the CAS number 5746-86-1, is an alkaloid derived from the tobacco plant, Nicotiana tabacum. It is a minor metabolite of nicotine, characterized by its structural similarity to nicotine but lacking the methyl group at the nitrogen atom. This compound exists as a racemic mixture, meaning it contains equal parts of its two enantiomers, which can exhibit different biological activities. (±)-Nornicotine is known to interact with nicotinic acetylcholine receptors, influencing neurotransmission and potentially affecting behaviors related to addiction and cognition. It is a colorless to pale yellow liquid with a characteristic odor and is soluble in water and organic solvents. The substance has garnered interest in pharmacological research due to its potential effects on the central nervous system and its role in tobacco-related studies. Safety data indicate that it should be handled with care, as it can be toxic in high doses, similar to other nicotine-related compounds.
Formula:C9H12N2
InChI:InChI=1S/C9H12N2/c1-3-8(7-10-5-1)9-4-2-6-11-9/h1,3,5,7,9,11H,2,4,6H2
InChI key:InChIKey=MYKUKUCHPMASKF-UHFFFAOYSA-N
SMILES:C1(CCCN1)C=2C=CC=NC2
Synonyms:- (2S)-2-pyridin-3-ylpyrrolidinium
- (RS)-Nornicotine
- (±)-1′-Demethylnicotine
- 1-Hexopyranuronosyl-3-(1-Methyl-5-Oxopyrrolidin-2-Yl)Pyridinium
- 2-(3-Pyridinyl)pyrrolidine
- 3-(2-Pyrrolidinyl)Pyridine
- 3-(Pyrrolidin-2-Yl)Pyridine
- Nicotine, 1′-demethyl-, (±)-
- Pyridine, 3-(2-pyrrolidinyl)-
- (R,S)-Nornicotine
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 15 products.
(±)-Nornicotine
CAS:Formula:C9H12N2Purity:>98.0%(GC)Color and Shape:Colorless to Light yellow clear liquidMolecular weight:148.21Nicotine Related Compound F (3-(pyrrolidin-2-yl)pyridine)
CAS:Vegetable alkaloids, natural or reproduced by synthesis, their salts and other derivatives, nesoiFormula:C9H12N2Color and Shape:Colorless Translucent Oily LiquidMolecular weight:148.100053-(2-Pyrrolidinyl)Pyridine
CAS:Formula:C9H12N2Purity:95%Color and Shape:LiquidMolecular weight:148.2050Nicotine USP Related Compound F (rac-Nicotine EP Impurity F)
CAS:Formula:C9H12N2Color and Shape:Colorless LiquidMolecular weight:148.213-[(2RS)-Pyrrolidin-2-yl]pyridine ((RS)-Nornicotine)
CAS:Controlled ProductFormula:C9H12N2Color and Shape:NeatMolecular weight:148.203-(Pyrrolidin-2-yl)pyridine
CAS:3-(Pyrrolidin-2-yl)pyridineFormula:C9H12N2Purity:98%Color and Shape: clear. faint yellow liquidMolecular weight:148.20498g/mol(R,S)-Nornicotine
CAS:Controlled Product<p>Impurity Nicotine USP Related Compound F (3-(pyrrolidine-2-yl)pyridine)<br>Stability Light Sensitive<br>Applications (RS)-Nornicotine is a tobacco alkaloid and the major Nicotine (N412420) metabolite in brain. Nornicotine appears to activate different nAChR subtypes, has a better pharmacokinetic profile, and produces less toxicity than Nicotine. Nornicotine shows a significant analgesic activity. Nicotine USP Related Compound F (3-(pyrrolidine-2-yl)pyridine).<br>References Hecht, S., et al.: Carcinogenesis, 9, 875 (1988), Rivenson, A., et al.: Cancer Res., 48, 6912 (1988), Hoffmann, D., et al.: Chem. Res. Toxicol., 14, 767 (2001), Kool, J., et al.: J. Med. Chem., 49, 3287 (2006), Kool, J., et al.: Drug Metab. Dispos., 35, 640 (2007),<br></p>Formula:C9H12N2Color and Shape:Colourless To Light YellowMolecular weight:148.20(R,S)-Nornicotine (1 mg/mL in Methanol)
CAS:Controlled ProductFormula:C9H12N2Color and Shape:ColourlessMolecular weight:148.20(R,S)-Nornicotine
CAS:(R,S)-Nornicotine is an enantiomeric mixture of nornicotine, which is an alkaloid compound. It is derived from tobacco plants, specifically as a metabolite of nicotine during the curing and fermentation processes. This compound is known for its interactions with nicotinic acetylcholine receptors (nAChRs) in the brain. It acts by binding to these receptors and modulating neural activity, influencing neurotransmitter release and synaptic plasticity.Formula:C9H12N2Purity:Min. 95%Color and Shape:Colorless PowderMolecular weight:148.21 g/mol3-(Pyrrolidin-2-yl)pyridine
CAS:Formula:C9H12N2Purity:95%Color and Shape:LiquidMolecular weight:148.209
![3-[(2RS)-Pyrrolidin-2-yl]pyridine ((RS)-Nornicotine)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F86%2Fthumb%2FMM0517.13.jpg&w=3840&q=75)
