CAS 57460-41-0

Talinolol

Description:

Talinolol, with the CAS number 57460-41-0, is a beta-adrenergic antagonist primarily used in the treatment of hypertension and certain heart conditions. It is characterized by its selective action on beta-1 adrenergic receptors, which makes it effective in reducing heart rate and myocardial contractility. This selectivity helps minimize side effects commonly associated with non-selective beta-blockers. Talinolol is known for its long half-life, allowing for once-daily dosing, which enhances patient compliance. The compound is typically administered orally and is well-absorbed in the gastrointestinal tract. Its pharmacokinetics may be influenced by factors such as age, liver function, and concomitant medications. Additionally, Talinolol exhibits a favorable safety profile, though potential side effects can include fatigue, dizziness, and bradycardia. As with all medications, it is essential for patients to consult healthcare professionals for personalized advice and monitoring while using Talinolol.

Formula: C₂₀H₃₃N₃O₃

InChI: InChI=1S/C20H33N3O3/c1-20(2,3)21-13-17(24)14-26-18-11-9-16(10-12-18)23-19(25)22-15-7-5-4-6-8-15/h9-12,15,17,21,24H,4-8,13-14H2,1-3H3,(H2,22,23,25)

InChI key: InChIKey=MXFWWQICDIZSOA-UHFFFAOYSA-N

SMILES: O(CC(CNC(C)(C)C)O)C1=CC=C(NC(NC2CCCCC2)=O)C=C1

Synonyms:

• 1-(4-Cyclohexylureidophenoxy)-2-hydroxy-3-tert-butylaminopropane
• 1-[3-(3-Cyclohexylureido)phenoxy]-3-(tert-butylamino)-2-propanol
• 1-[4-(Cyclohexylureido)phenoxy]-3-(tert-butylamino)-2-propanol
• 1-{4-[3-(tert-Butylamino)-2-hydroxypropoxy]phenyl}-3-cyclohexylurea
• 57460-41-0
• Cordanum
• N-Cyclohexyl-N′-[4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]phenyl]urea
• Racemic talinolol
• Urea, N-cyclohexyl-N′-[4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]phenyl]-
• Talinolol

(-)-Talinolol

CAS: 57460-41-0, 71369-59-0

Formula: C₂₀H₃₃N₃O₃

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 363.50

Ref: 3B-T4139

Talinolol

CAS: 57460-41-0

Formula: C₂₀H₃₃N₃O₃

Color and Shape: White To Off-White Solid

Molecular weight: 363.50

Ref: 4Z-T-651

Talinolol

CAS: 57460-41-0

Talinolol

Purity: ≥98%

Molecular weight: 363.49g/mol

Ref: 54-BUP02678

Talinolol

CAS: 57460-41-0

(±)-Talinolol is a selective β1 adrenoceptor antagonist well known for its cardioprotective and antihypertensive activity.

Formula: C₂₀H₃₃N₃O₃

Purity: 98.8%

Color and Shape: Solid

Molecular weight: 363.49

Ref: TM-T21640

rac-Talinolol

Controlled Product

CAS: 57460-41-0

Applications Selective β1-adrenergic blocker structurally related to Practolol. Antihypertensive; antiarrhythmic.
References Assmann, I., et al.: Curr. Med. Res. Opin., 13, 325 (1995), Trausch, B., et al.: Biopharm. Drug Dispos., 16, 403 (1995),

Formula: C₂₀H₃₃N₃O₃

Color and Shape: White To Light Pink

Molecular weight: 363.49

Ref: TR-T005000