CAS 57460-41-0: Talinolol

Description: Talinolol, with the CAS number 57460-41-0, is a beta-adrenergic antagonist primarily used in the treatment of hypertension and certain heart conditions. It is characterized by its selective action on beta-1 adrenergic receptors, which makes it effective in reducing heart rate and myocardial contractility. This selectivity helps minimize side effects commonly associated with non-selective beta-blockers. Talinolol is known for its long half-life, allowing for once-daily dosing, which enhances patient compliance. The compound is typically administered orally and is well-absorbed in the gastrointestinal tract. Its pharmacokinetics may be influenced by factors such as age, liver function, and concomitant medications. Additionally, Talinolol exhibits a favorable safety profile, though potential side effects can include fatigue, dizziness, and bradycardia. As with all medications, it is essential for patients to consult healthcare professionals for personalized advice and monitoring while using Talinolol.

Formula: C₂₀H₃₃N₃O₃

InChI: InChI=1S/C20H33N3O3/c1-20(2,3)21-13-17(24)14-26-18-11-9-16(10-12-18)23-19(25)22-15-7-5-4-6-8-15/h9-12,15,17,21,24H,4-8,13-14H2,1-3H3,(H2,22,23,25)

InChI key: InChIKey=MXFWWQICDIZSOA-UHFFFAOYSA-N

SMILES: O=C(NC1=CC=C(OCC(O)CNC(C)(C)C)C=C1)NC2CCCCC2

Synonyms:

• 1-(4-Cyclohexylureidophenoxy)-2-hydroxy-3-tert-butylaminopropane
• 1-[3-(3-Cyclohexylureido)phenoxy]-3-(tert-butylamino)-2-propanol
• 1-[4-(Cyclohexylureido)phenoxy]-3-(tert-butylamino)-2-propanol
• 1-{4-[3-(tert-Butylamino)-2-hydroxypropoxy]phenyl}-3-cyclohexylurea
• 57460-41-0
• Cordanum
• N-Cyclohexyl-N′-[4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]phenyl]urea
• Racemic talinolol
• Urea, N-cyclohexyl-N′-[4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]phenyl]-
• Talinolol

(-)-Talinolol

CAS: 57460-41-071369-59-0

• Formula: C₂₀H₃₃N₃O₃
• Purity: >95.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 363.50

Talinolol

CAS: 57460-41-0

• Formula: C₂₀H₃₃N₃O₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 363.50

Talinolol

CAS: 57460-41-0

• Purity: ≥98%
• Molecular weight: 363.49g/mol

Talinolol

CAS: 57460-41-0

(±)-Talinolol is a selective β1 adrenoceptor antagonist well known for its cardioprotective and antihypertensive activity.

• Formula: C₂₀H₃₃N₃O₃
• Purity: 98.80%
• Color and Shape: Solid
• Molecular weight: 363.49

rac-Talinolol

CAS: 57460-41-0

Applications Selective β1-adrenergic blocker structurally related to Practolol. Antihypertensive; antiarrhythmic. References Assmann, I., et al.: …

• Formula: C₂₀H₃₃N₃O₃
• Color and Shape: White To Light Pink
• Molecular weight: 363.49

Talinolol

CAS: 57460-41-0

Talinolol is a p-glycoprotein (p-gp) inhibitor that has been shown to be effective against infectious …

• Formula: C₂₀H₃₃N₃O₃
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 363.49 g/mol