CAS 57470-78-7

Celipolol Hydrochloride

Description:

Celipolol Hydrochloride is a pharmacological agent primarily classified as a beta-blocker, specifically a selective beta-1 adrenergic antagonist with additional properties that may influence beta-2 receptors. It is utilized in the management of hypertension and certain cardiovascular conditions due to its ability to reduce heart rate and myocardial contractility. The substance is characterized by its hydrochloride salt form, which enhances its solubility in water, facilitating its administration and absorption in the body. Celipolol exhibits a unique dual action, as it not only blocks beta-adrenergic receptors but also possesses vasodilatory effects, which can contribute to lowering blood pressure. Its chemical structure includes a phenolic moiety, which is significant for its biological activity. The pharmacokinetics of Celipolol indicate a moderate half-life, allowing for once or twice-daily dosing in clinical settings. As with any medication, potential side effects may include fatigue, dizziness, or gastrointestinal disturbances, and it is essential to monitor patients for any adverse reactions during treatment.

Formula: C₂₀H₃₄ClN₃O₄

InChI: InChI=1/C20H33N3O4.ClH/c1-7-23(8-2)19(26)22-15-9-10-18(17(11-15)14(3)24)27-13-16(25)12-21-20(4,5)6;/h9-11,16,21,25H,7-8,12-13H2,1-6H3,(H,22,26);1H

InChI key: InChIKey=VKJHTUVLJYWAEY-UHFFFAOYSA-N

SMILES: O(CC(CNC(C)(C)C)O)C1=C(C(C)=O)C=C(NC(N(CC)CC)=O)C=C1.Cl

Synonyms:

• 3-{3-Acetyl-4-[3-(Tert-Butylamino)-2-Hydroxypropoxy]Phenyl}-1,1-Diethylurea Hydrochloride (1:1)
• Celectol
• Celiprolol HCL
• Celiprolol Hydrochloride
• Corliprol
• NSC 324509
• Rev 5320A
• Selecor
• St 1396
• Tenoloc
• Urea, N′-[3-acetyl-4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]phenyl]-N,N-diethyl-, hydrochloride (1:1)
• Urea, N′-[3-acetyl-4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]phenyl]-N,N-diethyl-, monohydrochloride
• rhc-5320a
• ffhcl
• clorhidratodeceliprolol
• st1396hydrochloride
• 3-(3-acetyl-4-(3-tert-butylamino-2-hydroxypropoxy)phenyl)-1,1-diethylharnsto
• st1396clorhidrato
• Celipolol Hydrochloride
• celiprololclorhidrato
• 3-[3-acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl]-1,1-diethylurea hydrochloride
• Urea, N-3-acetyl-4-3-(1,1-dimethylethyl)amino-2-hydroxypropoxyphenyl-N,N-diethyl-, monohydrochloride
• 3-(3-acetil-4-(3-tert-butilamino-2-hidroxipropoxi)fenil)-1,1-dietilureahcl
• st1396hydrochlorid
• 3-(3-acetyl-4-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)phenyl)-1,1-ure
• selectrol
• CELIPOLOLHYDROCHLORIDE(SUBJECTTOPATENTFREE)
• 3-(3-acetyl-4-(3-tert-butylamino-2-hydroxypropoxy)phenyl)-1,1-diethylureahyd
• 3-[3-acetyl-4-[3-[(tert-butyl)amino]-2-hydroxypropoxy]phenyl]-1,1-diethyluronium chloride

Celiprolol Hydrochloride

CAS: 57470-78-7

Color and Shape: Neat

Ref: 61-FOR0128.00

Celiprolol Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS: 57470-78-7

Color and Shape: Single Solution

Ref: 61-AMP0128.00-01

CELIPROLOL HYDROCHLORIDE CRS

CAS: 57470-78-7

CELIPROLOL HYDROCHLORIDE CRS

Formula: C₂₀H₃₃N₃O₄

Color and Shape: Powder

Molecular weight: 379.4937

Ref: 41-Y0000311

Celiprolol hydrochloride

CAS: 57470-78-7

Celiprolol hydrochloride

Formula: C₂₀H₃₃N₃O₄HCl

Purity: 99.6%

Color and Shape: Off-White

Molecular weight: 415.22378

Ref: 47-757

3-(3-Acetyl-4-(3-(tert-butylamino)-2-hydroxypropoxy)phenyl)-1,1-diethylurea hydrochloride

CAS: 57470-78-7

Formula: C₂₀H₃₄ClN₃O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 415.9547

Ref: IN-DA019FVD

Celiprolol HCl

CAS: 57470-78-7

Formula: C₂₀H₃₃N₃O₄·HCl

Molecular weight: 379.50 36.46

Ref: 4Z-C-213004

Celiprolol Hydrochloride

CAS: 57470-78-7

Color and Shape: Neat

Ref: 86-MM0128.00

(S)-(-)-Celiprolol Hydrochloride

Controlled Product

CAS: 57470-78-7

Applications (S)-(-)-Celiprolol Hydrochloride is a cardioselective β1-adrenergic blocker (1,2,3). It is also an antihypertensive and antianginal agent.
References (1) Meininger, C., et al.: Biochem. J., 349, 353 (2000) (2) Ruan, H., et al.: Diabetes, 51, 1319 (2002) (3) Liao, Y., et al.: Circulation, 110, 692 (2004)

Formula: C₂₀H₃₃N₃O₄·ClH

Color and Shape: Neat

Molecular weight: 415.95

Ref: TR-C254495

(R)-(+)-Celiprolol Hydrochloride

Controlled Product

CAS: 57470-78-7

Applications Cardioselective β1-adrenergic blocker. Antihypertensive, antianginal.
References Mazzo, D.J., et al.: Anal. Profiles Drug Subs., 20, 237 (1991), Meininger, C., et al.: Biochem. J., 349, 353 (2000), Ruan, H., et al.: Diabetes, 51, 1319 (2002), Liao, Y., et al.: Circulation, 110, 692 (2004),

Formula: C₂₀H₃₃N₃O₄·ClH

Color and Shape: Neat

Molecular weight: 415.95

Ref: TR-C254490

Celiprolol Hydrochloride

Controlled Product

CAS: 57470-78-7

Applications Celiprolol is a cardioselective β1-adrenergic blocker. Antihypertensive, antianginal.
References Mazzo, D.J., et al.: Anal. Profiles Drug Subs., 20, 237 (1991), Meininger, C., et al.: Biochem. J., 349, 353 (2000), Ruan, H., et al.: Diabetes, 51, 1319 (2002), Liao, Y., et al.: Circulation, 110, 692 (2004),

Formula: C₂₀H₃₃N₃O₄·ClH

Color and Shape: Off-White

Molecular weight: 415.95

Ref: TR-C254500

Celiprolol hydrochloride

CAS: 57470-78-7

Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity.

Formula: C₂₀H₃₃N₃O₄·HCl

Color and Shape: White Crystalline Solid

Molecular weight: 415.96

Ref: TM-T1244