CAS 575-74-6

Buclosamide

Description:

Buclosamide, with the CAS number 575-74-6, is a chemical compound that belongs to the class of sulfonamides. It is primarily recognized for its use as an anthelmintic agent, particularly in veterinary medicine, where it is effective against various parasitic infections. The compound exhibits a sulfonamide functional group, which is characteristic of its mechanism of action, often involving the inhibition of folic acid synthesis in microorganisms. Buclosamide is typically administered in a solid form and is known for its relatively low toxicity profile in target organisms. Its solubility and stability can vary depending on environmental conditions, which can influence its efficacy and application. Additionally, the compound's pharmacokinetics, including absorption, distribution, metabolism, and excretion, are crucial for determining its therapeutic effectiveness. Overall, buclosamide serves as an important tool in managing parasitic diseases in livestock, contributing to animal health and productivity.

Formula: C₁₁H₁₄ClNO₂

InChI: InChI=1S/C11H14ClNO2/c1-2-3-6-13-11(15)9-5-4-8(12)7-10(9)14/h4-5,7,14H,2-3,6H2,1H3,(H,13,15)

InChI key: InChIKey=ZGJHIFYEQJEUKA-UHFFFAOYSA-N

SMILES: C(NCCCC)(=O)C1=C(O)C=C(Cl)C=C1

Synonyms:

• 4-Chloro-2-hydroxybenzoic acid-n-butylamide
• Benzamide, N-butyl-4-chloro-2-hydroxy-
• Demycin
• Fungit
• N-butyl-4-chloro-2-hydroxybenzamide
• N-butyl-4-chlorosalicylamide
• Salicylamide, N-butyl-4-chloro-
• Buclosamide

N-Butyl-4-chloro-2-hydroxybenzamide

CAS: 575-74-6

N-Butyl-4-chloro-2-hydroxybenzamide is a hydroxyl analog of the drug clobetasol. It has been used to treat bowel disease, and as an implanting agent in biological studies. It also has anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. N-Butyl-4-chloro-2-hydroxybenzamide can be used for the treatment of microbial infections such as infectious diseases caused by Mycobacterium tuberculosis or Escherichia coli. The drug has also been shown to have antiocclusive effects on the intestines and to reduce intestinal secretions. N-Butyl-4-chloro-2 hydroxybenzamide is taken orally and it is metabolized in the liver by CYP3A4 enzymes.

Formula: C₁₁H₁₄ClNO₂

Purity: Min. 95%

Molecular weight: 227.69 g/mol

Ref: 3D-AAA57574

Buclosamide

CAS: 575-74-6

Buclosamide is a topical antimycotic agent that can be used in dermatomycoses [1].

Formula: C₁₁H₁₄ClNO₂

Color and Shape: Solid

Molecular weight: 227.69

Ref: TM-T60287

Buclosamide

CAS: 575-74-6

Color and Shape: Neat

Ref: 61-FOR1842.00