CAS 57526-81-5

(-)-Prenalterol

Description:

(-)-Prenalterol, with the CAS number 57526-81-5, is a synthetic compound classified as a beta-adrenergic agonist. It is primarily used in the treatment of certain cardiovascular conditions, particularly for its ability to stimulate beta-1 adrenergic receptors, leading to increased heart rate and contractility. This compound is characterized by its chiral nature, with the "(-)" designation indicating its specific stereochemistry, which is crucial for its biological activity. (-)-Prenalterol exhibits a relatively short half-life and is metabolized in the liver, which influences its pharmacokinetics. The compound is typically administered in a clinical setting, and its efficacy can be influenced by factors such as dosage and individual patient response. Additionally, (-)-Prenalterol may have side effects common to beta-agonists, including potential cardiovascular effects like tachycardia or arrhythmias. Its chemical structure includes a phenolic group and an aliphatic chain, contributing to its interaction with adrenergic receptors. Overall, (-)-Prenalterol is an important agent in the pharmacological management of heart-related conditions.

Formula: C₁₂H₁₉NO₃

InChI: InChI=1/C12H19NO3/c1-9(2)13-7-11(15)8-16-12-5-3-10(14)4-6-12/h3-6,9,11,13-15H,7-8H2,1-2H3

InChI key: InChIKey=ADUKCCWBEDSMEB-NSHDSACASA-N

SMILES: O(C[C@H](CNC(C)C)O)C1=CC=C(O)C=C1

Synonyms:

• (-)-(S)-1-(p-Hydroxyphenoxy)-3-(isopropylamino)-2-propanol
• (S)-4-(2-Hydroxy-3-(isopropylamino)propoxy)phenol
• (S)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]phenol
• (S)-Prenalterol
• 260-791-5
• 4-[(2S)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]phenol
• 4-[2-Hydroxy-3-(Propan-2-Ylamino)Propoxy]Phenol
• 4-{[(2S)-2-hydroxy-3-(propan-2-ylamino)propyl]oxy}phenol
• Cgp 7760B
• H 133/22
• Hyprenan
• Phenol, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-, (S)-
• Phenol, 4-[(2S)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]-
• S-Varbian
• phenol, 4-[[(2S)-2-hydroxy-3-[(1-methylethyl)amino]propyl]oxy]-
• Prenalterol
• Prenalterolprenalterol
• cgp7760b
• h133/22

(S)-4-(2-Hydroxy-3-(isopropylamino)propoxy)phenol

CAS: 57526-81-5

Formula: C₁₂H₁₉NO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 225.2842

Ref: IN-DA00E95Q

(±)-Prenalterol

CAS: 57526-81-5

(±)-Prenalterol

Purity: ≥98%

Molecular weight: 225.28g/mol

Ref: 54-BUP06735

Prenalterol

CAS: 57526-81-5

Formula: C₁₂H₁₉NO₃

Molecular weight: 225.28

Ref: 7W-GP5825

Prenalterol

Controlled Product

CAS: 57526-81-5

Applications Prenalterol is a β1-adrenergic agonist and used as an cardiotonic (1,2,3).
References (1) Ma, C., et al.: J. Pharm. Biomed. Anal., 47, 677 (2008)(2) Scheiber, J., et al.: J. Med. Chem., 52, 3103 (2009(3) Broadley, K., et al.: Biochem. Pharmacol., 80, 1537 (2010)

Formula: C₁₂H₁₉NO₃

Color and Shape: Neat

Molecular weight: 225.28

Ref: TR-P712700

Prenalterol

CAS: 57526-81-5

Prenalterol is a drug that can be used to treat congestive heart failure and high blood pressure. It belongs to the class of 2-adrenergic receptor agonists, which are drugs that stimulate the sympathetic nervous system. Prenalterol has been shown to have a positive effect on the cardiovascular system by increasing cardiac output. This drug also has an anti-inflammatory effect, which may be due to its ability to inhibit protein synthesis genes in cells. Prenalterol has also been shown to reduce post-myocardial infarction remodeling by reducing myocardial fibrosis, although it does not affect the incidence of myocardial infarcts.

Formula: C₁₂H₁₉NO₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 225.28 g/mol

Ref: 3D-FP27157

Prenalterol-d7

Controlled Product

CAS: 57526-81-5

Applications Labelled Prenalterol (P712700). P712700 Prenalterol is a β1-adrenergic agonist. Prenalterol is used as an cardiotonic.
References Ma, C., et al.: J. Pharm. Biomed. Anal., 47, 677 (2008), Scheiber, J., et al.: J. Med. Chem., 52, 3103 (2009), Broadley, K., et al.: Biochem. Pharmacol., 80, 1537 (2010),

Formula: C₁₂D₇H₁₂NO₃

Color and Shape: Neat

Molecular weight: 232.327

Ref: TR-P712702

(±)-Prenalterol

CAS: 57526-81-5

(±)-Prenalterol (H 80/62) is an agonist of beta-2- and beta-1-adrenergic receptors and is used to study chronic congestive heart failure.

Formula: C₁₂H₁₉NO₃

Purity: 99.73%

Color and Shape: Solid

Molecular weight: 225.28

Ref: TM-T25984