CAS 57531-37-0

2-Chloro-4-nitroimidazole

Description:

2-Chloro-4-nitroimidazole is a chemical compound characterized by its imidazole ring, which is a five-membered heterocyclic structure containing two nitrogen atoms. This compound features a chlorine atom at the second position and a nitro group at the fourth position of the imidazole ring, contributing to its reactivity and potential biological activity. It is typically a solid at room temperature and may exhibit moderate solubility in polar solvents. The presence of the nitro group often imparts significant electrophilic properties, making it useful in various chemical reactions, including nucleophilic substitutions. 2-Chloro-4-nitroimidazole is of interest in medicinal chemistry, particularly for its potential antimicrobial and antifungal properties. Safety considerations should be taken into account when handling this compound, as it may pose health risks, including irritation to skin and eyes, and potential toxicity. Proper storage and disposal methods are essential to mitigate environmental impact and ensure safety in laboratory settings.

Formula: C₃H₂ClN₃O₂

InChI: InChI=1S/C3H2ClN3O2/c4-3-5-1-2(6-3)7(8)9/h1H,(H,5,6)

InChI key: InChIKey=BOJZBRDIZUHTCE-UHFFFAOYSA-N

SMILES: N(=O)(=O)C=1NC(Cl)=NC1

Synonyms:

• 1H-Imidazole, 2-Chloro-4-Nitro-
• 1H-Imidazole, 2-chloro-5-nitro-
• 1H-Imidazole,2-chloro-4-nitro-(9CI)
• 2-Chloro-4(5)-nitroimidazole
• 2-Chloro-4-Nitro-1H-Imidazole, 98+%
• 2-Chloro-4-nitro-1H-imidazole
• 2-Chloro-5-Nitro-1H-Imidazole
• P₂₁
• Timtec-Bb Sbb000100
• P21
• 2-Chloro-4-nitroimidazole

2-Chloro-5-nitroimidazole, 95%

CAS: 57531-37-0

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Formula: C₃H₂ClN₃O₂

Purity: 95%

Molecular weight: 147.52

Ref: 02-H61141

2-Chloro-5-nitroimidazole

CAS: 57531-37-0

Formula: C₃H₂ClN₃O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 147.5199

Ref: IN-DA003GXU

2-Chloro-4-nitroimidazole

CAS: 57531-37-0

Formula: C₃H₂ClN₃O₂

Molecular weight: 147.52

Ref: 7W-GK6231

2-Chloro-4-nitro-1H-imidazole

CAS: 57531-37-0

2-Chloro-4-nitro-1H-imidazole

Formula: C₃H₂ClN₃O₂

Purity: ≥95%

Color and Shape: pale yellow powder

Molecular weight: 147.52g/mol

Ref: 54-OR2577

2-Chloro-4-nitroimidazole

CAS: 57531-37-0

Radiosensitiser in hypoxic tumours

Formula: C₃H₂ClN₃O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 147.52 g/mol

Ref: 3D-FC20104

2-Chloro-5-nitro-1H-imidazole

CAS: 57531-37-0

Formula: C₃H₂ClN₃O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 147.52

Ref: 10-F040152

2-Chloro-4-nitroimidazole

Controlled Product

CAS: 57531-37-0

Applications 4-Nitroimidazole derivative with poetenial use as radiosensitizers of hypoxic cells. It is used in the preparation of antitubercular nitroimidazoles.
References Widel, M. et al.: Neoplasma, 3, 241 (1987); Kim, P. et al.: J. Med. Chem., 52, 1317 (2009);

Formula: C₃H₂ClN₃O₂

Color and Shape: Off-White To Beige

Molecular weight: 147.52

Ref: TR-C373935