CAS 57564-91-7

Nitrosoglutathione

Description:

Nitrosoglutathione, with the CAS number 57564-91-7, is a chemical compound formed by the reaction of nitric oxide with glutathione, a tripeptide composed of glutamate, cysteine, and glycine. This compound is characterized by its role as a signaling molecule in biological systems, particularly in the modulation of cellular processes such as apoptosis, inflammation, and oxidative stress. Nitrosoglutathione is known for its ability to donate nitric oxide, which can influence various physiological functions and contribute to the regulation of blood flow and immune responses. It exists in a relatively stable form under physiological conditions but can undergo decomposition or react with other biomolecules. The compound is also of interest in research related to cardiovascular health and neuroprotection, as it may play a role in protecting cells from oxidative damage. Its unique properties make it a significant subject of study in biochemistry and pharmacology, particularly in understanding the mechanisms of nitric oxide signaling in health and disease.

Formula: C₁₀H₁₆N₄O₇S

InChI: InChI=1S/C10H16N4O7S/c11-5(10(19)20)1-2-7(15)13-6(4-22-14-21)9(18)12-3-8(16)17/h5-6H,1-4,11H2,(H,12,18)(H,13,15)(H,16,17)(H,19,20)/t5-,6-/m0/s1

InChI key: InChIKey=HYHSBSXUHZOYLX-WDSKDSINSA-N

SMILES: [C@H](C(NCC(O)=O)=O)(NC(CC[C@@H](C(O)=O)N)=O)CSN=O

Synonyms:

• <span class="text-smallcaps">L</smallcap>-γ-Glutamyl-S-nitroso-<smallcap>L</span>-cysteinylglycine
• Glycine, <span class="text-smallcaps">L</smallcap>-γ-glutamyl-S-nitroso-<smallcap>L</span>-cysteinyl-
• Glycine, N-(N-<span class="text-smallcaps">L</smallcap>-γ-glutamyl-S-nitroso-<smallcap>L</span>-cysteinyl)-
• Nitrosoglutathione
• RVC 588 (peptide)
• Rvc 588
• S-Nitroso-<span class="text-smallcaps">L</span>-glutathione
• S-Nitrosoglutathione
• S-Nitrosylglutathione
• L-γ-Glutamyl-S-nitroso-L-cysteinylglycine
• Glycine, L-γ-glutamyl-S-nitroso-L-cysteinyl-

(S)-2-Amino-5-(((R)-1-((carboxymethyl)amino)-3-(nitrosothio)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid

CAS: 57564-91-7

Formula: C₁₀H₁₆N₄O₇S

Purity: 95%

Color and Shape: Solid

Molecular weight: 336.3216

Ref: IN-DA003CKW

(S)-2-Amino-5-(((R)-1-((Carboxymethyl)Amino)-3-(Nitrosothio)-1-Oxopropan-2-Yl)Amino)-5-Oxopentanoic Acid

CAS: 57564-91-7

(S)-2-Amino-5-(((R)-1-((Carboxymethyl)Amino)-3-(Nitrosothio)-1-Oxopropan-2-Yl)Amino)-5-Oxopentanoic Acid

Purity: 95%

Molecular weight: 336.32g/mol

Ref: 54-OR1027255

Nitrosoglutathione

CAS: 57564-91-7

Nitrosoglutathione

Purity: ≥98%

Molecular weight: 336.32g/mol

Ref: 54-BUP06420

S-Nitrosoglutathione

CAS: 57564-91-7

Formula: C₁₀H₁₆N₄O₇S

Purity: ≥ 98.0%

Color and Shape: Pink crystalline powder

Molecular weight: 336.32

Ref: 7W-GL7950

S-Nitroso Glutathione

CAS: 57564-91-7

Formula: C₁₀H₁₆N₄O₇S

Molecular weight: 336.32

Ref: 4Z-PG-2534

Nitrosoglutathione

CAS: 57564-91-7

Nitrosoglutathione (GSNO) is an endogenous transnitrosation donor involved in S-nitrosation of a variety of cellular proteins.

Formula: C₁₀H₁₆N₄O₇S

Purity: 99.61% - 99.68%

Color and Shape: Pink Powder

Molecular weight: 336.32

Ref: TM-T19930

S-Nitroso-L-glutathione

Controlled Product

CAS: 57564-91-7

Stability Hygroscopic
Applications A carrier of nitric oxide, relaxing smooth muscle and inhibiting platelet activation.
References Thompson, C., et al.: Toxicol., App. Pharmacol., 233, 355 (2008), Bateman, R., et al.: J. Biol. Chem., 283, 35756 (2008), Foster, M., et al.: Biochem., 48, 792 (2009),

Formula: C₁₀H₁₆N₄O₇S

Purity: >90%

Color and Shape: Neat

Molecular weight: 336.32

Ref: TR-N527500

S-Nitroso Glutathione

CAS: 57564-91-7

Formula: C₁₀H₁₆N₄O₇S

Molecular weight: 336.32

Ref: ST-EA-CP-G55005