CAS 57568-80-6

4-Morpholinecarboximidamide, N-cyclohexyl-N′-tricyclo[3.3.1.13,7]dec-1-yl-, hydrochloride (1:1)

Description:

4-Morpholinecarboximidamide, N-cyclohexyl-N′-tricyclo[3.3.1.13,7]dec-1-yl-, hydrochloride (1:1), with CAS number 57568-80-6, is a chemical compound characterized by its complex structure, which includes a morpholine ring and a tricyclic decane moiety. This compound typically exhibits properties associated with both amides and imidamides, which may influence its solubility and reactivity. The presence of the hydrochloride indicates that it is a salt form, which often enhances its stability and solubility in aqueous solutions. The morpholine group contributes to its potential as a pharmacophore, while the cyclohexyl and tricyclic components may impart unique steric and electronic properties. Such compounds are often investigated for their biological activity, particularly in medicinal chemistry, where they may serve as potential drug candidates. However, specific applications and biological effects would depend on further empirical studies. Safety data and handling precautions should be referenced from material safety data sheets (MSDS) due to the potential hazards associated with chemical substances.

Formula: C₂₁H₃₅N₃O·ClH

InChI: InChI=1S/C21H35N3O.ClH/c1-2-4-19(5-3-1)22-20(24-6-8-25-9-7-24)23-21-13-16-10-17(14-21)12-18(11-16)15-21;/h16-19H,1-15H2,(H,22,23);1H

InChI key: InChIKey=FZALCKUJYZCDOX-UHFFFAOYSA-N

SMILES: N(=C(NC1CCCCC1)N2CCOCC2)C34CC5CC(C3)CC(C4)C5.Cl

Synonyms:

• 4-Morpholinecarboximidamide, N-cyclohexyl-N'-tricyclo[3.3.1.1~3,7~]dec-1-yl-, hydrochloride (1:1)
• 4-Morpholinecarboximidamide, N-cyclohexyl-N′-tricyclo[3.3.1.1^3,7]dec-1-yl-, hydrochloride (1:1)
• 4-Morpholinecarboximidamide, N-cyclohexyl-N′-tricyclo[3.3.1.1^3,7]dec-1-yl-, monohydrochloride
• N'-(Adamantan-1-yl)-N-cyclohexylmorpholine-4-carboximidamide hydrochloride (1:1)
• N-[1-Adamantyl]-N-cyclohexyl-4-morpholinecarboxamidine hydrochloride
• Pnu 37883A
• Pnu 37887A
• U 37883A
• 4-Morpholinecarboximidamide, N-cyclohexyl-N′-tricyclo[3.3.1.13,7]dec-1-yl-, monohydrochloride
• 4-Morpholinecarboximidamide, N-cyclohexyl-N′-tricyclo[3.3.1.13,7]dec-1-yl-, hydrochloride (1:1)

PNU 37883 hydrochloride

CAS: 57568-80-6

PNU 37883 hydrochloride is a potent inhibitor of the ATP-sensitive potassium channel that blocks the opening of the channel in response to changes in intracellular ATP levels. PNU 37883 hydrochloride blocks both the α and β subunits of these channels, which are necessary for transmitting signals from outside to inside cells. It has been shown to inhibit papillary muscle contractions and reduce blood pressure in vivo. PNU 37883 hydrochloride also inhibits renal glomerular filtration rate and cardiac contractility, as well as inhibiting atp-sensitive K+ channels in mesenteric artery. This drug has also been shown to be effective against hepatitis C virus infection, both in vitro and in vivo. As an additional mechanism, it has been shown to increase pluripotent cells such as embryonic stem cells or induced pluripotent stem cells by blocking cyclase activity.

Formula: C₂₁H₃₅N₃O·HCl

Purity: Min. 95%

Molecular weight: 381.98 g/mol

Ref: 3D-HCA56880

PNU 37883 hydrochloride

CAS: 57568-80-6

Kir6 (KATP) channel antagonist

Formula: C₂₁H₃₆ClN₃O

Purity: 98%

Color and Shape: Solid

Molecular weight: 381.98

Ref: TM-T23169