CAS 576-68-1

Mannomustine

Description:

Mannomustine, with the CAS number 576-68-1, is a chemical compound that belongs to the class of alkylating agents, specifically a derivative of mustine. It is characterized by its ability to form covalent bonds with DNA, leading to cross-linking and subsequent disruption of DNA replication and transcription processes. This mechanism of action makes mannomustine a candidate for use in cancer therapy, particularly in the treatment of certain types of tumors. The compound is typically a white to off-white solid and is soluble in various organic solvents. Its chemical structure includes a mustine moiety, which contributes to its reactivity and biological activity. As with many alkylating agents, mannomustine may exhibit cytotoxic effects, and its use is associated with potential side effects, including myelosuppression and other toxicities. Due to its pharmacological properties, mannomustine is of interest in medicinal chemistry and oncology research, although its clinical application may be limited by safety and efficacy considerations.

Formula: C₁₀H₂₂Cl₂N₂O₄

InChI: InChI=1/C10H22Cl2N2O4/c11-1-3-13-5-7(15)9(17)10(18)8(16)6-14-4-2-12/h7-10,13-18H,1-6H2/t7-,8-,9-,10-/m1/s1

InChI key: InChIKey=MQXVYODZCMMZEM-ZYUZMQFOSA-N

SMILES: [C@H]([C@@H]([C@@H](CNCCCl)O)O)([C@@H](CNCCCl)O)O

Synonyms:

• 1,6-Bis(chloroethylaino)-1,6-bis-deoxy-<span class="text-smallcaps">D</span>-mannitol
• 1,6-Bis[(2-Chloroethyl)Amino]-1,6-Dideoxyhexitol
• 1,6-Bis[(2-chloroethyl)amino]-1,6-dideoxy-<span class="text-smallcaps">D</span>-mannitol
• 1,6-bis(2-chloroethylamino)-1,6-dideoxy-D-mannitol
• <span class="text-smallcaps">D</span>-Mannitol, 1,6-bis[(2-chloroethyl)amino]-1,6-dideoxy-
• BCM (cytostatic)
• Mannitol mustard
• Mannitol, 1,6-bis[(2-chloroethyl)amino]-1,6-dideoxy-, <span class="text-smallcaps">D</span>-
• Mannomustin
• D-Mannitol, 1,6-bis[(2-chloroethyl)amino]-1,6-dideoxy-
• Mannitol, 1,6-bis[(2-chloroethyl)amino]-1,6-dideoxy-, D-
• 1,6-Bis[(2-chloroethyl)amino]-1,6-dideoxy-D-mannitol
• Mannomustine
• mannomustine USP/EP/BP

1,6-Bis[(2-chloroethyl)amino]-1,6-dideoxy-D-mannitol

Controlled Product

CAS: 576-68-1

Formula: C₁₀H₂₂Cl₂N₂O₄

Color and Shape: Neat

Molecular weight: 305.2

Ref: TR-C576680