CAS 57653-26-6

Fenobam

Description:

Fenobam is a chemical compound that acts as a selective antagonist of the metabotropic glutamate receptor subtype 5 (mGluR5). It is primarily studied for its potential therapeutic effects in treating anxiety and other neuropsychiatric disorders. Fenobam is characterized by its ability to modulate glutamatergic signaling, which is crucial in various brain functions, including mood regulation and cognition. The compound has shown promise in preclinical and clinical studies, demonstrating anxiolytic effects without the sedative properties commonly associated with traditional anxiolytics. Its chemical structure includes a bicyclic framework, contributing to its pharmacological activity. Fenobam is typically administered orally and has a favorable pharmacokinetic profile, although its exact mechanism of action and long-term effects are still under investigation. As with any pharmacological agent, potential side effects and interactions with other medications should be considered. Overall, Fenobam represents a novel approach in the field of psychopharmacology, targeting specific receptor pathways to alleviate symptoms of anxiety and related disorders.

Formula: C₁₁H₁₁ClN₄O₂

InChI: InChI=1/C11H11ClN4O2/c1-16-6-9(17)14-10(16)15-11(18)13-8-4-2-3-7(12)5-8/h2-5H,6H2,1H3,(H2,13,14,15,17,18)

InChI key: InChIKey=DWPQODZAOSWNHB-UHFFFAOYSA-N

SMILES: N(C(NC1=CC(Cl)=CC=C1)=O)C2=NC(=O)CN2C

Synonyms:

• 1-(3-Chlorophenyl)-3-(1-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)urea
• 1-(3-chlorophenyl)-3-[(2E)-1-methyl-4-oxoimidazolidin-2-ylidene]urea
• 57653-26-6
• N-(3-Chlorophenyl)-N′-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)urea
• Urea, N-(3-chlorophenyl)-N′-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)-
• urea, N-(3-chlorophenyl)-N'-[(2E)-1-methyl-4-oxo-2-imidazolidinylidene]-
• Fenobam
• 1-(3-Chlorophenyl)-3-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)urea
• N-(3-CHLOROPHENYL)-N'-(4,5-DIHYDRO-1-METHYL-4-OXO-1H-IMIDAZOLE-2-YL)UREA
• Mcn-3377

Fenobam

CAS: 57653-26-6

Fenobam shows inverse agonist activity which blocks the mGlu5 receptor basal activity(IC50: 84 nM).

Formula: C₁₁H₁₁ClN₄O₂

Purity: 99.93%

Color and Shape: Solid

Molecular weight: 266.68

Ref: TM-T15275

Fenobam

CAS: 57653-26-6

Formula: C₁₁H₁₁ClN₄O₂

Purity: 98%

Molecular weight: 266.6836

Ref: IN-DA01E4RI

Fenobam

CAS: 57653-26-6

Formula: C₁₁H₁₁ClN₄O₂

Molecular weight: 266.68

Ref: 7W-GL3040

Fenobam

CAS: 57653-26-6

Fenobam

Purity: ≥98%

Molecular weight: 266.68g/mol

Ref: 54-BUP15246

Fenobam

CAS: 57653-26-6

M03843 - Fenobam

Formula: C₁₁H₁₁ClN₄O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 266.69

Ref: 10-M03843

Fenobam

Controlled Product

CAS: 57653-26-6

Formula: C₁₁H₁₁ClN₄O₂

Color and Shape: Neat

Molecular weight: 266.684

Ref: TR-F248603