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CAS 57672-79-4

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Baccatin VI

Description:
Baccatin VI is a naturally occurring chemical compound classified as a diterpene, specifically derived from the Pacific yew tree (Taxus brevifolia). It is known for its role as a precursor in the synthesis of the anticancer drug paclitaxel (Taxol). Baccatin VI exhibits a complex molecular structure characterized by multiple rings and functional groups, which contribute to its biological activity. The compound has demonstrated significant cytotoxic properties, making it of interest in cancer research. Its mechanism of action involves the stabilization of microtubules, thereby inhibiting cell division. Baccatin VI is typically isolated through extraction and purification processes from yew tree bark or needles. Due to its potential therapeutic applications, it has been the subject of various studies aimed at understanding its pharmacological effects and optimizing its use in cancer treatment. However, the extraction of Baccatin VI raises concerns regarding sustainability and the conservation of yew tree populations, prompting research into synthetic alternatives and biosynthetic pathways.
Formula:C37H46O14
InChI:InChI=1S/C37H46O14/c1-18-25(46-19(2)38)16-37(44)32(50-33(43)24-13-11-10-12-14-24)30-35(9,26(47-20(3)39)15-27-36(30,17-45-27)51-23(6)42)31(49-22(5)41)29(48-21(4)40)28(18)34(37,7)8/h10-14,25-27,29-32,44H,15-17H2,1-9H3/t25-,26-,27+,29+,30-,31-,32-,35+,36-,37+/m0/s1
InChI key:InChIKey=UJFKTEIDORFVQS-SKNQRQHZSA-N
SMILES:O(C(C)=O)[C@]12[C@@]3([C@](C)([C@@H](OC(C)=O)[C@H](OC(C)=O)C=4C(C)(C)[C@](O)([C@H]3OC(=O)C5=CC=CC=C5)C[C@H](OC(C)=O)C4C)[C@@H](OC(C)=O)C[C@]1(OC2)[H])[H]
Synonyms:
  • Baccatin VI
  • 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete-4,5,6,9,11,12,12b-heptol, 2a,3,4,4a,5,6,9,10,12,12a-decahydro-4a,8,13,13-tetramethyl-, 4,5,6,9,12b-pentaacetate 12-benzoate, [2aR-(2aα,4β,4aβ,5α,6β,9α,11α,12α,12aα,12bα)]-
  • 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete-4,5,6,9,11,12,12b-heptol, 2a,3,4,4a,5,6,9,10,12,12a-decahydro-4a,8,13,13-tetramethyl-, 4,5,6,9,12b-pentaacetate 12-benzoate, (2aR,4S,4aS,5R,6R,9S,11S,12S,12aR,12bS)-
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Found 4 products.
  • Baccatin VI
    Indagoo
    + Info

    Baccatin VI

    CAS:
    Formula:C37H46O14
    Purity:98.0%
    Color and Shape:Solid
    Molecular weight:714.7527

    Ref: IN-DA00EBI5

    5mg
    To inquire
  • Baccatin VI
    Targetmol
    + Info

    Baccatin VI

    CAS:
    Baccatin VI possesses significant antinociceptive activity against p-benzoquinone-induced abdominal contractions.
    Formula:C37H46O14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:714.75

    Ref: TM-TN3476

  • Baccatin VI
    Biopurify
    + Info

    Baccatin VI

    CAS:
    Formula:C37H46O14
    Purity:95%~99%
    Molecular weight:714.761

    Ref: BP-SBP04235

    ne
    To inquire
  • Baccatin VI
    TRC
    + Info

    Baccatin VI

    Controlled Product
    CAS:
    <p>Applications A taxane derivative, a neoplasm inhibitor to ovarian and breast cancers found in Taxus species.<br>References Katkovcinova, Z., et al.: J. Biosci., 63, 721 (2008), Tian, J., et al.: J. Pharm. Sci., 97, 3100 (2008), Miao, Z., et al.: App. Biochem. Microbiol., 45, 81 (2009),<br></p>
    Formula:C37H46O14
    Color and Shape:Neat
    Molecular weight:714.75

    Ref: TR-B101030

    5mg
    353.00€
    50mg
    2,397.00€