CAS 57734-69-7

α,α-Bis(2-methylphenyl)-1-azabicyclo[2.2.2]octane-3-methanol

Description:

α,α-Bis(2-methylphenyl)-1-azabicyclo[2.2.2]octane-3-methanol, with CAS number 57734-69-7, is a chemical compound characterized by its bicyclic structure, which includes a nitrogen atom integrated into a bicyclo[2.2.2]octane framework. This compound features two 2-methylphenyl groups attached to the nitrogen atom, contributing to its lipophilicity and potential biological activity. The presence of a hydroxymethyl group at the 3-position enhances its solubility in polar solvents and may influence its reactivity and interaction with biological targets. The compound's structural features suggest potential applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting the central nervous system. Its unique bicyclic structure may also confer specific stereochemical properties, which can be crucial for its biological efficacy. Overall, α,α-Bis(2-methylphenyl)-1-azabicyclo[2.2.2]octane-3-methanol represents a complex organic molecule with interesting chemical and pharmacological properties, warranting further investigation in various chemical and biological contexts.

Formula: C₂₂H₂₇NO

InChI: InChI=1S/C22H27NO/c1-16-7-3-5-9-19(16)22(24,20-10-6-4-8-17(20)2)21-15-23-13-11-18(21)12-14-23/h3-10,18,21,24H,11-15H2,1-2H3

InChI key: InChIKey=OXDOWGVJMITMJL-UHFFFAOYSA-N

SMILES: C(O)(C1C2CCN(C1)CC2)(C3=C(C)C=CC=C3)C4=C(C)C=CC=C4

Synonyms:

• (1-Aza-bicyclo[2.2.2]oct-3-yl)-di-o-tolyl-methanol
• 1-Azabicyclo[2.2.2]Oct-3-Yl[Bis(2-Methylphenyl)]Methanol
• 1-Azabicyclo[2.2.2]octane-3-methanol, α,α-bis(2-methylphenyl)-
• 3-Quinuclidinemethanol, alpha,alpha-di-o-tolyl-
• Benzhydrol, 2,2'-dimethyl-alpha-(3-quinuclidinyl)-
• Bicarphene
• Brn 1548429
• Sequifenadina
• Sequifenadina [Spanish]
• Sequifenadine [INN]
• Sequifenadinum
• Sequifenadinum [Latin]
• Unii-C7Q3Tbr3Fp
• alpha,alpha-Di-o-tolyl-3-quinuclidinemethanol
• α,α-Bis(2-methylphenyl)-1-azabicyclo[2.2.2]octane-3-methanol
• Sequifenadine

Sequifenadine

CAS: 57734-69-7

Sequifenadine has the potential in researching of inflammatory eye disease with allergic symptoms that is a H1-antihistamine [1] [2].

Formula: C₂₂H₂₇NO

Color and Shape: Solid

Molecular weight: 321.46

Ref: TM-T60864