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CAS 5776-45-4

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Estradiol, 17-palmitate

Description:
Estradiol 17-palmitate is an ester derivative of estradiol, a potent estrogen hormone, and palmitic acid. This compound is characterized by its molecular structure, which includes a steroid backbone typical of estrogens, modified by the addition of a palmitate group. This modification enhances its lipophilicity, allowing for improved absorption and prolonged action in biological systems. Estradiol 17-palmitate is often utilized in hormone replacement therapies and contraceptive formulations due to its estrogenic activity. It exhibits properties such as promoting the development of female secondary sexual characteristics and regulating various physiological processes, including the menstrual cycle and reproductive functions. The compound is typically administered via intramuscular injection or as part of transdermal delivery systems. Its pharmacokinetics are influenced by the esterification, leading to a slower release compared to unmodified estradiol, which can be beneficial in therapeutic applications. Safety and efficacy are critical considerations in its use, necessitating careful monitoring in clinical settings.
Formula:C34H54O3
InChI:InChI=1S/C34H54O3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-33(36)37-32-22-21-31-30-19-17-26-25-27(35)18-20-28(26)29(30)23-24-34(31,32)2/h18,20,25,29-32,35H,3-17,19,21-24H2,1-2H3/t29-,30-,31+,32+,34+/m1/s1
InChI key:InChIKey=XQKLZLWOOGGXMV-KWXXMMNJSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(O)=CC4)(CC1)[H])[H])(CC[C@@H]2OC(CCCCCCCCCCCCCCC)=O)[H]
Synonyms:
  • (17Beta)-3-Hydroxyestra-1,3,5(10)-Trien-17-Yl Hexadecanoate
  • 17β-Estradiol monopalmitate
  • Esmopal
  • Estra-1,3,5(10)-triene-3,17-diol (17β)-, 17-hexadecanoate
  • Estra-1,3,5(10)-triene-3,17beta-diol 17-palmitate
  • Estradiol 17-hexadecanoate
  • Estradiol 17-monopalmitate
  • Estradiol monopalmitate
  • Estradiol, 17-palmitate
  • Palmitic acid, 17-ester with estradiol
  • Unii-1Q5Y448Xt0
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Found 2 products.
  • Estradiol 17-Palmitate
    TRC
    + Info

    Estradiol 17-Palmitate

    Controlled Product
    CAS:
    Formula:C34H54O3
    Color and Shape:Neat
    Molecular weight:510.791

    Ref: TR-E888840

    1g
    1,509.00€
  • Estradiol 17-Palmitate-d31
    TRC
    + Info

    Estradiol 17-Palmitate-d31

    Controlled Product
    CAS:
    <p>Applications Estradiol 17-Palmitate-d31 is the isotope analog of Estradiol 17-Palmitate. Estradiol 17-Palmitate is a metabolite of estradiol (E888000) which is the major estrogen secreted by the premenopausal ovary.<br>References Salole, E.G., et al.: Anal. Profiles Drug Subs., 15, 283 (1986), Lievertz, R.W., et al.: Am. J. Obstet. Gynecol., 156, 1289 (1987),<br></p>
    Formula:C34H23D31O3
    Color and Shape:Neat
    Molecular weight:399.48

    Ref: TR-E888842

    25mg
    1,530.00€