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CAS 57773-63-4

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Triptorelin

Description:
Triptorelin is a synthetic peptide and a gonadotropin-releasing hormone (GnRH) analog, primarily used in the treatment of hormone-sensitive conditions such as prostate cancer, endometriosis, and precocious puberty. It is characterized by its ability to inhibit the secretion of gonadotropins (LH and FSH) from the pituitary gland, leading to a decrease in testosterone and estrogen levels. Triptorelin is typically administered via injection and has a prolonged action compared to natural GnRH due to its structural modifications, which enhance its stability and bioavailability. The substance is known for its efficacy in managing hormone-related disorders, but it may also have side effects, including hot flashes, mood changes, and potential impacts on bone density with long-term use. Its chemical structure includes a sequence of amino acids that mimic the natural hormone, allowing it to bind effectively to GnRH receptors. As a therapeutic agent, Triptorelin is classified under the category of hormonal therapies and is subject to regulation in various medical contexts.
Formula:C66H88N18O15
InChI:InChI=1/C42H59N11O9.C22H25N7O4.C2H4O2/c1-24(2)19-31(37(58)50-30(9-5-16-46-42(44)45)41(62)53-17-6-10-34(53)40(61)48-23-35(43)56)51-39(60)33(21-26-22-47-29-8-4-3-7-28(26)29)52-38(59)32(49-36(57)15-18-54)20-25-11-13-27(55)14-12-25;23-20(31)17(7-12-9-25-15-4-2-1-3-14(12)15)28-22(33)18(8-13-10-24-11-26-13)29-21(32)16-5-6-19(30)27-16;1-2(3)4/h3-4,7-8,11-14,22,24,30-34,47,54-55H,5-6,9-10,15-21,23H2,1-2H3,(H2,43,56)(H,48,61)(H,49,57)(H,50,58)(H,51,60)(H,52,59)(H4,44,45,46);1-4,9-11,16-18,25H,5-8H2,(H2,23,31)(H,24,26)(H,27,30)(H,28,33)(H,29,32);1H3,(H,3,4)/t30-,31-,32-,33+,34-;16-,17-,18-;/m00./s1
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