CAS 57808-66-9: Domperidone

Description:Domperidone is a medication primarily used as an antiemetic and gastroprokinetic agent. It functions by blocking dopamine receptors, particularly in the gastrointestinal tract and the chemoreceptor trigger zone of the brain, which helps alleviate nausea and vomiting. The chemical formula of domperidone is C22H24ClN5O2, and it features a piperidine ring, a chlorobenzamide moiety, and a butyrophenone structure. Domperidone is typically administered orally and is known for its relatively low central nervous system penetration, which minimizes neurological side effects compared to other dopamine antagonists. It is often prescribed for conditions such as gastroparesis and to manage nausea associated with certain treatments, including chemotherapy. The substance is classified as a prescription medication in many countries and is subject to regulatory oversight due to its pharmacological effects and potential side effects, including cardiovascular risks. Overall, domperidone is valued for its efficacy in promoting gastric motility and controlling nausea while maintaining a favorable safety profile when used appropriately.

Formula:C₂₂H₂₄ClN₅O₂

InChI:InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30)

InChI key:InChIKey=FGXWKSZFVQUSTL-UHFFFAOYSA-N

SMILES:O=C1NC=2C=CC=CC2N1CCCN3CCC(N4C(=O)NC5=CC(Cl)=CC=C54)CC3

Synonyms:
2H-Benzimidazol-2-one, 5-chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-
5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazole-2-one
Alpha-[2-(Diisopropylamino) Ethyl]-Alpha-Phenyl-2-Pyridineacetamide
Domcolic
Domperi 10 DT
Domperidon
Domperidona
Euciton
Evoxin
See more synonyms
Gastronorm
Kw 5338
Mod
Motilium
Motillium
Motinorm costi
Nauzelin
Nauzelin Ds
Nomit
Nsc 299589
Peridon
Peridys
R 33812
Domperidone

Found 14 products.

Product data	Purity	Price range	Estimated delivery
Domperidone REF: 3B-D4125CAS: 57808-66-9	>98.0%(T)(HPLC)	103.00 €~338.00 €	Mon 07 Apr 25
Domperidone REF: 02-J63681CAS: 57808-66-9	- - -	To inquire	Tue 08 Apr 25
Domperidone CRS REF: 41-D2955000CAS: 57808-66-9	- - -	115.00 €	Mon 14 Apr 25
5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one REF: IN-DA0037JPCAS: 57808-66-9	95%	23.00 €~557.00 €	Mon 14 Apr 25
Domperidone REF: TM-T0082CAS: 57808-66-9	98% - 99.82%	46.00 €~145.00 €	Mon 14 Apr 25
Domperidone REF: 7W-GP3849CAS: 57808-66-9	≥ 99.0% (dried substance)	38.00 €~185.00 €	Tue 15 Apr 25
Domperidone REF: 4Z-D-491CAS: 57808-66-9	- - -	To inquire	Tue 15 Apr 25
Domperidone REF: 54-BUP16115CAS: 57808-66-9	99.72%	65.00 €~293.00 €	Tue 15 Apr 25
Domperidone REF: 54-OR1029321CAS: 57808-66-9	- - -	32.00 €~1,187.00 €	Tue 15 Apr 25
Domperidone REF: 86-MM0107.00-0250CAS: 57808-66-9	- - -	4,472.00 €	Thu 17 Apr 25
Domperidone REF: 04-C13081600CAS: 57808-66-9	- - -	100.00 €	Thu 17 Apr 25
Domperidone REF: TR-D531100CAS: 57808-66-9	- - -	94.00 €~376.00 €	Thu 24 Apr 25
Domperidone, pharma grade REF: 3D-BD164379CAS: 57808-66-9	Min. 95%	144.00 €~793.00 €	Fri 25 Apr 25
Domperidone REF: 3D-FD31879CAS: 57808-66-9	98.0 To 101.0%	121.00 €~1,195.00 €	Tue 10 Jun 25