CAS 57808-66-9
:Domperidone
Description:
Domperidone is a medication primarily used as an antiemetic and gastroprokinetic agent. It functions by blocking dopamine receptors, particularly in the gastrointestinal tract and the chemoreceptor trigger zone of the brain, which helps alleviate nausea and vomiting. The chemical formula of domperidone is C22H24ClN5O2, and it features a piperidine ring, a chlorobenzamide moiety, and a butyrophenone structure. Domperidone is typically administered orally and is known for its relatively low central nervous system penetration, which minimizes neurological side effects compared to other dopamine antagonists. It is often prescribed for conditions such as gastroparesis and to manage nausea associated with certain treatments, including chemotherapy. The substance is classified as a prescription medication in many countries and is subject to regulatory oversight due to its pharmacological effects and potential side effects, including cardiovascular risks. Overall, domperidone is valued for its efficacy in promoting gastric motility and controlling nausea while maintaining a favorable safety profile when used appropriately.
Formula:C22H24ClN5O2
InChI:InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30)
InChI key:InChIKey=FGXWKSZFVQUSTL-UHFFFAOYSA-N
SMILES:O=C1N(C=2C(N1)=CC(Cl)=CC2)C3CCN(CCCN4C=5C(NC4=O)=CC=CC5)CC3
Synonyms:- 2H-Benzimidazol-2-one, 5-chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-
- 5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
- 5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazole-2-one
- Alpha-[2-(Diisopropylamino) Ethyl]-Alpha-Phenyl-2-Pyridineacetamide
- Domcolic
- Domperi 10 DT
- Domperidon
- Domperidona
- Euciton
- Evoxin
- Gastronorm
- Kw 5338
- Mod
- Motilium
- Motillium
- Motinorm costi
- Nauzelin
- Nauzelin Ds
- Nomit
- Nsc 299589
- Peridon
- Peridys
- R 33812
- See more synonyms
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Found 16 products.
Domperidone
CAS:<p>Peripheral dopamine receptor antagonist that does not cross the blood-brain barrier</p>Formula:C22H24ClN5O2Molecular weight:425.91DOMPERIDONE CRS
CAS:<p>DOMPERIDONE CRS</p>Formula:C22H24ClN5O2Color and Shape:White. Whitish. Powder.Molecular weight:425.91135-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one
CAS:Formula:C22H24ClN5O2Purity:95%Color and Shape:SolidMolecular weight:425.9113Domperidone
CAS:<p>Domperidone (R33812)(Motilium) is a dopamine blocker and an antidopaminergic reagent.</p>Formula:C22H24ClN5O2Purity:98% - 99.82%Color and Shape:SolidMolecular weight:425.91Domperidone
CAS:Formula:C22H24ClN5O2Purity:≥ 99.0% (dried substance)Color and Shape:White to off-white powderMolecular weight:425.91Domperidone
CAS:Formula:C22H24ClN5O2Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:425.92Domperidone
CAS:<p>Applications A novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic. Domperidone (Motilium) is a dopamine blocker and an antidopaminergic reagent.<br>References Baudry, M., et al.: Arch. Pharmacol., 308, 231 (1979), Ennis, C., et al.: J. Pharm. Pharmacol., 31, 14 (1979), Brogden, R.N., Drugs, 24, 360 (1982),<br></p>Formula:C22H24ClN5O2Color and Shape:White To Off-WhiteMolecular weight:425.91Domperidone, pharma grade
CAS:<p>Dopamine D2 receptor antagonist</p>Formula:C22H24ClN5O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:425.91 g/molDomperidone
CAS:<p>Dopamine D2 receptor antagonist</p>Formula:C22H24ClN5O2Purity:98.0 To 101.0%Molecular weight:425.91 g/mol
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