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CAS 57847-69-5

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Cefedrolor

Description:
Cefedrolor, identified by the CAS number 57847-69-5, is a synthetic antibiotic belonging to the class of cephalosporins, which are characterized by their beta-lactam structure. This compound exhibits broad-spectrum antibacterial activity, making it effective against a variety of Gram-positive and Gram-negative bacteria. Cefedrolor works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. It is typically administered via injection and is used in the treatment of various infections, including respiratory tract infections, skin infections, and urinary tract infections. The pharmacokinetics of cefedrolor involve absorption, distribution, metabolism, and excretion, with its efficacy influenced by factors such as dosage and the specific bacterial strain. As with other antibiotics, the potential for resistance development is a concern, necessitating careful use and adherence to prescribed regimens. Side effects may include allergic reactions, gastrointestinal disturbances, and alterations in normal flora. Overall, cefedrolor represents an important therapeutic option in the arsenal against bacterial infections.
Formula:C16H16ClN3O5S
InChI:InChI=1/C16H16ClN3O5S/c1-6-5-26-15-11(14(23)20(15)12(6)16(24)25)19-13(22)10(18)7-2-3-9(21)8(17)4-7/h2-4,10-11,15,21H,5,18H2,1H3,(H,19,22)(H,24,25)/t10-,11-,15-/m1/s1
SMILES:CC1=C(C(=O)O)N2C(=O)[C@H]([C@H]2SC1)N=C([C@@H](c1ccc(c(c1)Cl)O)N)O
Synonyms:
  • Cefedrolor [INN]
  • (6R,7R)-7-((R)-2-Amino-2-(3-chloro-4-hydroxyphenyl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
  • Bmy 25154
  • Unii-O3Ty87Kjii
  • (6R,7R)-7-{[(2R)-2-amino-2-(3-chloro-4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
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