CAS 57898-80-3

N-Desbutyroyl Acebutolol

Description:

N-Desbutyroyl Acebutolol is a chemical compound that belongs to the class of beta-blockers, which are primarily used in the treatment of cardiovascular conditions. It is a derivative of acebutolol, characterized by the absence of a butyryl group, which influences its pharmacological properties. The compound typically exhibits properties such as moderate lipophilicity, allowing it to penetrate biological membranes effectively. Its mechanism of action involves selective inhibition of beta-adrenergic receptors, leading to decreased heart rate and myocardial contractility, making it useful in managing hypertension and arrhythmias. Additionally, N-Desbutyroyl Acebutolol may possess intrinsic sympathomimetic activity, which can provide a unique therapeutic profile compared to other beta-blockers. The compound is generally well-tolerated, but like other medications in its class, it may have side effects, including fatigue, dizziness, or gastrointestinal disturbances. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are essential for understanding its clinical applications and potential interactions with other drugs.

Formula: C₁₄H₂₂N₂O₃

Acebutolol EP Impurity D

CAS: 57898-80-3

Formula: C₁₄H₂₂N₂O₃

Molecular weight: 266.34

Ref: ST-EA-CP-A94004

Ethyl (E)-2-dodecenoate

CAS: 57898-80-3

Ethyl (E)-2-dodecenoate

Molecular weight: 226.36g/mol

Ref: 54-BUP20625

Acebutolol EP Impurity D

CAS: 57898-80-3

Formula: C₁₄H₂₂N₂O₃

Color and Shape: Yellow Solid

Molecular weight: 266.34

Ref: 4Z-A-169005

Deacyl acebutolol

CAS: 57898-80-3

Deacyl acebutolol is the major metabolite of Acebutolol.

Formula: C₁₄H₂₂N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 266.34

Ref: TM-T21021

rac-N-Desbutyroyl acebutolol

CAS: 57898-80-3

rac-N-Desbutyroyl acebutolol is a prodrug that is metabolized to the active form, acebutolol. The metabolism of rac-N-desbutyroyl acebutolol is mediated through cytochrome P450 (CYP) enzymes, specifically CYP2D6. Rac-N-desbutyroyl acebutolol has been shown to inhibit the growth of bacteria in vitro and in vivo. It has also been shown to have therapeutic effects on diabetic patients with high levels of fatty acids in their blood. Rac-N-desbutyroyl acebutolol has also been found to be effective for the treatment of patients with polycarboxylic acid exposure and dna replication diseases.

Formula: C₁₄H₂₂N₂O₃

Purity: Min. 95%

Molecular weight: 266.34 g/mol

Ref: 3D-IR27556