CAS 579-38-4

Diloxanide

Description:

Diloxanide is an antiprotozoal agent primarily used in the treatment of intestinal amoebiasis caused by Entamoeba histolytica. It is characterized by its chemical formula, which typically includes a combination of carbon, hydrogen, nitrogen, and oxygen atoms. The compound is known for its ability to inhibit the growth of the amoeba, thereby alleviating symptoms associated with the infection. Diloxanide is often administered in the form of its phosphate salt, enhancing its solubility and bioavailability. The substance exhibits moderate lipophilicity, which aids in its absorption in the gastrointestinal tract. Its mechanism of action involves disrupting the metabolic processes of the protozoan, leading to cell death. While generally well-tolerated, potential side effects may include gastrointestinal disturbances. Diloxanide is classified under the broader category of nitroimidazoles and is typically prescribed in conjunction with other medications for comprehensive treatment. As with any medication, it is essential to follow medical guidance regarding dosage and duration of treatment to ensure efficacy and minimize adverse effects.

Formula: C₉H₉Cl₂NO₂

InChI: InChI=1S/C9H9Cl2NO2/c1-12(9(14)8(10)11)6-2-4-7(13)5-3-6/h2-5,8,13H,1H3

InChI key: InChIKey=GZZZSOOGQLOEOB-UHFFFAOYSA-N

SMILES: N(C(C(Cl)Cl)=O)(C)C1=CC=C(O)C=C1

Synonyms:

• 2,2-Dichlor-4'-hydroxy-N-methylacetanilid
• 2,2-Dichlor-4'-hydroxy-N-methylacetanilid [IUPAC]
• 2,2-Dichloro-4'-hydroxy-N-methylacetanilide
• 2,2-dichloro-N-(4-hydroxyphenyl)-N-methylacetamide
• Acetamide, 2,2-dichloro-N-(4-hydroxyphenyl)-N-methyl-
• Acetanilide, 2,2-dichloro-4'-hydroxy-N-methyl-
• Ame-boots
• Amebamida
• Brn 2840273
• Dichloro-N-4-hydroxyphenyl-N-methylacetamide
• Diloxanid
• Diloxanida
• Diloxanida [INN-Spanish]
• Diloxanide [INN:BAN:DCF]
• Diloxanidum
• Diloxanidum [INN-Latin]
• Entamide
• M & B 4453
• N-Dichloroacetyl-N-methyl-p-hydroxyaniline
• Rd 3803
• Unii-89134Scm7M

Diloxanide

CAS: 579-38-4

Diloxanide

Purity: ≥95%

Molecular weight: 234.08g/mol

Ref: 54-BUP11794

Diloxanide

CAS: 579-38-4

Diloxanide (RD3803) is an endomoeba insecticide.

Formula: C₉H₉Cl₂NO₂

Purity: 99.27%

Color and Shape: Solid

Molecular weight: 234.08

Ref: TM-T31482

2,2-Dichloro-N-(4-hydroxyphenyl)-N-methylacetamide

CAS: 579-38-4

2,2-Dichloro-N-(4-hydroxyphenyl)-N-methylacetamide (FUROATE) is a synthetic antimicrobial agent that is structurally related to the furoate class of antibiotics. FUROATE has been shown to be effective against urothelial carcinoma cells and minimal toxic in animals. It binds to the fatty acid component of bacterial cell membranes and causes rapid lysis. FUROATE is used as an analytical reagent for the determination of hydroxyl groups in organic solutes. The detection limit of this test is 0.1 ppm. Monoclonal antibodies can be generated against FUROATE for use as diagnostic or therapeutic agents for infectious diseases, such as HIV infection.

Formula: C₉H₉Cl₂NO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 234.08 g/mol

Ref: 3D-AAA57938