CAS 58-33-3

Promethazine hydrochloride

Description:

Promethazine hydrochloride is an antihistamine medication primarily used to treat allergies, motion sickness, and nausea, as well as to induce sedation. It belongs to the phenothiazine class of compounds and functions by blocking histamine H1 receptors, thereby alleviating allergic symptoms. This substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various formulations, including tablets, syrups, and injectable forms. Promethazine hydrochloride has a relatively low molecular weight and exhibits a melting point that allows for easy handling and formulation. Its pharmacological effects include sedation, antiemetic properties, and the ability to reduce motion sickness. However, it may cause side effects such as drowsiness, dry mouth, and dizziness. Caution is advised when administering this medication, particularly in young children and the elderly, due to the potential for respiratory depression. Overall, promethazine hydrochloride is a versatile medication with a well-established profile in clinical use.

Formula: C₁₇H₂₁ClN₂S

InChI: InChI=1/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H/p-1

InChI key: InChIKey=XXPDBLUZJRXNNZ-UHFFFAOYSA-N

SMILES: C(C(N(C)C)C)N1C=2C(SC=3C1=CC=CC3)=CC=CC2.Cl

Synonyms:

• 10-[2-(Dimethylamino)propyl]phenothiazine hydrochloride
• 10H-Phenothiazine-10-ethanamine, N,N,α-trimethyl-, hydrochloride (1:1)
• Anergan 25
• Anergan 50
• Atosil
• Diprasine
• Diprazin
• Dorme
• Duplamin
• Fellozine
• Fenazil
• Fenergan
• Genphen
• Hiberna
• Himazin
• Kinetosin
• Lergigan
• Mepergan
• N,N,α-Trimethyl-10H-phenothiazine-10-ethanamine monohydrochloride
• Nsc 231688
• Phanergan D
• Phena
• Phencen
• Phenergan
• Phenergan VC
• Phenothiazine, 10-[2-(dimethylamino)propyl]-, monohydrochloride
• Pipolfen
• Pipolphen
• Plletia
• Promasun
• Prometazina, Clorhidrato
• Promethazine Hydrochloride
• Promethazine chloride
• Promethazine monohydrochloride
• Promethazine, chlorhydrate
• Promethazinhydrochlorid
• Promethazinium chloride
• Prorex
• Prothazine
• Provigan
• Pyrethia
• Remsed
• Romergan
• Romergan hydrochloride
• Promethazine HCl
• 10H-Phenothiazine-10-ethanamine, N,N,α-trimethyl-, monohydrochloride
• 10H-phenothiazine-10-ethanamine, N,N,α-trimethyl-, chloride
• N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine hydrochloride (1:1)
• N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine
• n-(2-dimethylaminopropyl-1)phenothiazinehydrochloride
• n-(2’-dimethylamino-2’-methyl)ethylphenothiazinehydrochloride
• 10-(2-dimethylamino-1-propyl)phenothiazine hydrochloride
• n,n,alpha-trimethyl-10h-phenothiazine-10-ethanaminmonohydrochloride
• 10-(2-(dimethylamino)propyl)phenothiazinemonohydrochloride
• 10-(2-(dimethylamino)propyl)-phenothiazinmonohydrochloride
• hl8700
• ganphen
• 10-(3-dimethylaminoisopropyl)phenothiazinehydrochloride

Promethazine HCl - Bio-X ™

Controlled Product

CAS: 58-33-3

Promethazine is an antihistamine drug that is used to treat allergic conditions, nausea and vomiting. This drug is an antagonist of histamine receptors and NDMA receptors. Antagonism of NDMA receptors help to aid in better sleep and anxiety relief. Additionally, antagonism of histamine receptors aid in preventing nausea and vomiting.

Formula: C₁₇H₂₁ClN₂S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 320.88 g/mol

Ref: 3D-BP166198

Promethazine Hydrochloride

CAS: 58-33-3

Formula: C₁₇H₂₀N₂SHCl

Molecular weight: 284.4 : 36.5

Ref: ST-EA-CP-P86008