CAS 58-58-2
:Puromycin hydrochloride
Description:
Puromycin hydrochloride is an antibiotic compound that is derived from the bacterium *Streptomyces alboniger*. It is primarily known for its role as a protein synthesis inhibitor, specifically targeting the ribosomal machinery of both prokaryotic and eukaryotic cells. The compound functions by mimicking the structure of aminoacyl-tRNA, leading to premature termination of polypeptide chains during translation. Puromycin hydrochloride is typically presented as a white to off-white crystalline powder, soluble in water and various organic solvents. Its molecular formula includes elements such as carbon, hydrogen, nitrogen, and oxygen, contributing to its biological activity. In laboratory settings, puromycin is widely used in molecular biology for selecting genetically modified cells, as it can effectively eliminate non-resistant cells. However, due to its potent effects, handling requires caution, and appropriate safety measures should be observed. Overall, puromycin hydrochloride serves as a valuable tool in research, particularly in studies related to gene expression and protein synthesis.
Formula:C22H29N7O5·2ClH
InChI:InChI=1S/C22H29N7O5.2ClH/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12;;/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32);2*1H/t14-,15+,16+,18+,22+;;/m0../s1
InChI key:InChIKey=MKSVFGKWZLUTTO-FZFAUISWSA-N
SMILES:O[C@H]1[C@H](N2C=3C(N=C2)=C(N(C)C)N=CN3)O[C@H](CO)[C@H]1NC([C@H](CC4=CC=C(OC)C=C4)N)=O.Cl
Synonyms:- Adenosine, 3′-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3′-deoxy-N,N-dimethyl-, hydrochloride (1:2)
- Adenosine, 3′-(α-amino-p-methoxyhydrocinnamamido)-3′-deoxy-N,N-dimethyl-, dihydrochloride, L-
- Adenosine, 3′-[[2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3′-deoxy-N,N-dimethyl-, dihydrochloride, (S)-
- Adenosine, 3′-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3′-deoxy-N,N-dimethyl-, dihydrochloride
- CL 16,536
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Found 15 products.
Puromycin dihydrochloride, 98%
CAS:<p>Puromycin dihydrochloride, 58-58-2, also known as stylomycin hydrochloride, is an aminoglycoside antibiotic which acts by inhibiting protein synthesis. Learn more.</p>Formula:C22H31Cl2N7O5Purity:98%Color and Shape:White to pale cream, PowderMolecular weight:544.43Puromycin dihydrochloride, 10 mg/ml in distilled water, sterile-filtered
CAS:<p>Puromycin, 58-58-2, is an aminoglycoside antibiotic produced by Streptomyces alboniger which acts by inhibiting protein synthesis. Learn more at Thermo Fisher Scientific.</p>Formula:C22H29N7O5Color and Shape:Clear colorless to pale cream, LiquidMolecular weight:471.52Adenosine,3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-, dihydrochloride
CAS:Formula:C22H31Cl2N7O5Purity:98%Color and Shape:SolidMolecular weight:544.4314Ref: IN-DA00IABE
1gTo inquire2gTo inquire5gTo inquire1mg43.00€5mg52.00€10mg73.00€25mg115.00€50mg182.00€100mg166.00€250mg504.00€Puromycin dihydrochloride
CAS:Puromycin dihydrochlorideFormula:C22H29N7O5·2ClHPurity:By hplc: 98.48% (Typical Value in Batch COA)Color and Shape: off-white powderMolecular weight:544.43g/molPuromycin dihydrochloride (animal free)
CAS:Puromycin dihydrochloride (animal free)Formula:C22H29N7O5·2ClHPurity:By hplc: 99.07% (Typical Value in Batch COA)Color and Shape: slightly pink powderMolecular weight:544.43g/molPuromycin dihydrochloride
CAS:Puromycin dihydrochloride, from Streptomyces alboniger, blocks protein synthesis, acting as an antineoplastic and antitrypanosomal agent.Formula:C22H31Cl2N7O5Purity:98.65% - 99.89%Color and Shape:Physical Description White Powder (Ntp 1992)Molecular weight:544.44Puromycin dihydrochloride
CAS:Formula:C22H29N7O5·2HClPurity:≥ 98.0%Color and Shape:White to off-white powderMolecular weight:544.44Puromycin Dihydrochloride
CAS:Controlled Product<p>Applications Puromycin is an aminonucleoside antibitotic. Puromycin acts as a protein synthesis inhibitor which interferes with translation by inhibiting ribosome functions. Puromycin is also a reversible inhibitor of dipeptidyl-peptidase II (serine peptidase) and cytosol alanyl aminopeptidase.<br>References Pestka, S. et al.: Ann. Rev. Micromiol., 8, 1559 (1997); Dando, P.M. et al.: Biomed. Health Res., 13, 88 (1997); McDonald, J.K. et al.: J. Biol. Chem., 243, 2028 (1968);<br></p>Formula:C22H29N7O5·2ClHColor and Shape:NeatMolecular weight:544.43Puromycin dihydrochloride
CAS:<p>Puromycin is active against both prokaryotic and eukaryotic cells. Puromycin resistance gene (pac) is a common choice for the selection of mammalian cells since its first application in 1988, especially for therapeutic proteins in mammalian cells where it was used to produce high levels of protein of interest. Puromycin can also be used as a selection marker for Archea.</p>Formula:C22H31Cl2N7O5Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:544.44 g/molPuromycin Dihydrochloride (PRM), 98%
CAS:Formula:C22H29N7O5·2HClPurity:min. 98%Color and Shape:White to pale yellow, PowderMolecular weight:544.44Puromycin Dihydrochloride (PRM) for cell culture, Endotoxin (BET) 10EU/mg
CAS:Formula:C22H29N7O5·2HClPurity:min. 98%Color and Shape:White to pale yellow, PowderMolecular weight:544.44Puromycin dihydrochloride
CAS:<p>M02245 - Puromycin dihydrochloride</p>Formula:C22H31Cl2N7O5Purity:98%Color and Shape:Solid, PowderMolecular weight:544.43Puromycin-D3 Dihydrochloride
CAS:Controlled Product<p>Applications Puromycin-D3 Dihydrochloride is a labelled analogue of Puromycin Dihydrochloride (P840320), an aminonucleoside antibitotic. Puromycin acts as a protein synthesis inhibitor which interferes with translation by inhibiting ribosome functions. Puromycin is also a reversible inhibitor of dipeptidyl-peptidase II (serine peptidase) and cytosol alanyl aminopeptidase.<br>References Pestka, S. et al.: Ann. Rev. Micromiol., 8, 1559 (1997); Dando, P.M. et al.: Biomed. Health Res., 13, 88 (1997); McDonald, J.K. et al.: J. Biol. Chem., 243, 2028 (1968);<br></p>Formula:C22H26D3N7O5•2(HCl)Color and Shape:NeatMolecular weight:474.53 + 2(36.46)
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