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CAS 58-93-5

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Hydrochlorothiazide

Description:
Hydrochlorothiazide is a thiazide diuretic commonly used in the treatment of hypertension and edema associated with heart failure, liver cirrhosis, and renal disorders. Its chemical formula is C7H8ClN3O4S, and it features a sulfonamide group, which is integral to its mechanism of action. Hydrochlorothiazide works by inhibiting the sodium-chloride symporter in the distal convoluted tubule of the nephron, leading to increased excretion of sodium and water, thereby reducing blood volume and lowering blood pressure. The substance is typically administered orally and is known for its relatively rapid onset of action. Hydrochlorothiazide is characterized by its moderate solubility in water and is often formulated in combination with other antihypertensive agents to enhance therapeutic efficacy. Common side effects may include electrolyte imbalances, particularly hypokalemia, and it may also affect glucose metabolism. As with any medication, it is essential to use hydrochlorothiazide under medical supervision to monitor for potential adverse effects and interactions with other drugs.
Formula:C7H8ClN3O4S2
InChI:InChI=1S/C7H8ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-2,10-11H,3H2,(H2,9,12,13)
InChI key:InChIKey=JZUFKLXOESDKRF-UHFFFAOYSA-N
SMILES:O=S1(=O)C=2C(=CC(Cl)=C(S(N)(=O)=O)C2)NCN1
Synonyms:
  • 3,4-Dihydrochlorothiazide
  • 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
  • 6-Chloro-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
  • 6-Chloro-7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide
  • 6-Chloro-7-sulfamoyl-3,4-dihydrobenzo-1,2,4-thiadiazine-1,1-dioxide
  • Acuretic
  • Apo-Hydro
  • Apresazide
  • Aquarius
  • Aquazide
  • See more synonyms
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products per page.Found 22 products.
  • Hydrochlorothiazide
    Biosynth
    + Info

    Hydrochlorothiazide

    Controlled Product
    CAS:
    Hydrochlorothiazide is a thiazide-sensitive NaCl cotransporter inhibitor. Due to its diuretic properties, hydrochlorothiazide can inhibit the transport of sodium chloride in the distal tubule in the nephron and, as a consequence, the concentration of Na is decreased. In combination with other substances, such as captopril, hydrochlorothiazide acts an antihypertensive to reduce high blood pressure.
    Formula:C7H8ClN3O4S2
    Purity:Min. 98 Area-%
    Color and Shape:White Powder
    Molecular weight:297.74 g/mol

    Ref: 3D-FH23880

    100g
    248.00€
    250g
    465.00€
    500g
    724.00€
    1kg
    882.00€
    2kg
    1,201.00€
  • Hydrochlorothiazide - Bio-X ™
    Biosynth
    + Info

    Hydrochlorothiazide - Bio-X ™

    Controlled Product
    CAS:
    Hydrochlorothiazide is a thiazide diuretic. It is used to treat high blood pressure and fluid retention. Hydrochlorothiazide lowers levels of electrolytes such as potassium, sodium, and chloride in the body by increasing the amount of water that is excreted. This drug has been shown to be effective in reducing disease activity and improving quality of life for patients with chronic inflammatory conditions such as rheumatoid arthritis and psoriasis.
    Formula:C7H8ClN3O4S2
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:297.74 g/mol

    Ref: 3D-BH164522

    100mg
    135.00€