CAS 5800-34-0

Glutaryl-L-phenylalanine p-nitroanilide

Description:

Glutaryl-L-phenylalanine p-nitroanilide, with the CAS number 5800-34-0, is a synthetic compound primarily used in biochemical research and as a substrate in enzyme assays. This compound features a glutaryl group, which is a five-carbon dicarboxylic acid derivative, linked to an L-phenylalanine moiety, an amino acid known for its role in protein synthesis and metabolism. The p-nitroanilide portion of the molecule is a common chromogenic group that can be used to detect enzymatic activity through colorimetric changes. The compound is typically characterized by its solubility in organic solvents and its stability under standard laboratory conditions. It is important in studies involving proteolytic enzymes, particularly in the assessment of enzyme kinetics and specificity. Safety data sheets should be consulted for handling and storage guidelines, as with any chemical substance, to ensure safe laboratory practices.

Formula: C₂₀H₂₁N₃O₆

InChI: InChI=1/C20H21N3O6/c24-18(7-4-8-19(25)26)22-17(13-14-5-2-1-3-6-14)20(27)21-15-9-11-16(12-10-15)23(28)29/h1-3,5-6,9-12,17H,4,7-8,13H2,(H,21,27)(H,22,24)(H,25,26)/t17-/m0/s1

InChI key: InChIKey=LFZGBNATHRHOKZ-KRWDZBQOSA-N

SMILES: [C@H](CC1=CC=CC=C1)(C(NC2=CC=C(N(=O)=O)C=C2)=O)NC(CCCC(O)=O)=O

Synonyms:

• 5-[[(1S)-2-[(4-Nitrophenyl)amino]-2-oxo-1-(phenylmethyl)ethyl]amino]-5-oxopentanoic acid
• Glutaramic acid, N-[α-[(p-nitrophenyl)carbamoyl]phenethyl]-, <span class="text-smallcaps">L</span>-
• Glutaryl-<span class="text-smallcaps">L</span>-phenylalanine 4-nitroanilide
• Glutaryl-<span class="text-smallcaps">L</span>-phenylalanine p-nitroanilide
• Gpana
• N-Glutaryl-<span class="text-smallcaps">L</span>-phenylalanine 4-nitroanilide
• N-Glutaryl-<span class="text-smallcaps">L</span>-phenylalanine p-nitroanilide
• N-Glutaryl-<span class="text-smallcaps">L</span>-phenylalanyl p-nitroanilide
• N-Glutaryl-L-Phenylalanine P-Nitroanilide
• Pentanoic acid, 5-[[(1S)-2-[(4-nitrophenyl)amino]-2-oxo-1-(phenylmethyl)ethyl]amino]-5-oxo-
• Pentanoic acid, 5-[[2-[(4-nitrophenyl)amino]-2-oxo-1-(phenylmethyl)ethyl]amino]-5-oxo-, (S)-
• Glutaramic acid, N-[α-[(p-nitrophenyl)carbamoyl]phenethyl]-, L-
• N-(4-Nitrophenyl)-Nα-(4-carboxybutyryl)phenylalaninamide
• 5-Hydroxy-5-oxopentanoyl-L-Phe-Nan
• 5-[[(2S)-1-(4-nitroanilino)-1-oxo-3-phenylpropan-2-yl]amino]-5-oxopentanoic acid
• Pentanoic acid, 5-(1S)-2-(4-nitrophenyl)amino-2-oxo-1-(phenylmethyl)ethylamino-5-oxo-
• (S)-5-[[1-benzyl-2-[(4-nitrophenyl)amino]-2-oxoethyl]amino]-5-oxovaleric acid
• N-Glutaryl-L-phenylalanyl p-nitroanilide
• H-GLUT-PHE-PNA
• N-α-Glutaryl-L-phenylalanine p-nitroanilide
• 5-[[(S)-2-[(4-Nitrophenyl)amino]-2-oxo-1-(phenylmethyl)ethyl]amino]-5-oxopentanoic acid
• GLUTARYL-PHE-PNA
• 5-[[(1S)-1-(benzyl)-2-keto-2-(4-nitroanilino)ethyl]amino]-5-keto-valeric acid
• N-GLUTARYL-L-PHE-BETA-NITROANILIDE
• 5-[[(2S)-1-[(4-nitrophenyl)amino]-1-oxo-3-phenyl-propan-2-yl]amino]-5-oxo-pentanoic acid
• H-GLUTARYL-PHE-PNA
• N-ALPHA-GLUTARYL-PHENYLALANINE P-NITROANILIDE
• Nα-(4-Carboxybutyryl)-N-(4-nitrophenyl)phenylalaninamide
• glutarylphenylalanine-4-nitroanilide
• GLUTARYL-PHENYLALANINE-PNA
• Glutaryl-L-phenylalanine p-nitroanilide
• GLUTARYL-L-PHENYLALANINE 4-NITROANILIDE

(S)-4-Amino-5-(((S)-1-((4-nitrophenyl)amino)-1-oxo-3-phenylpropan-2-yl)amino)-5-oxopentanoic acid

CAS: 5800-34-0

Formula: C₂₀H₂₁N₃O₆

Color and Shape: Solid

Molecular weight: 399.3972

Ref: IN-DA00ECTZ

N-GLUTARYL-L-PHENYLALANINE P-NITROANILIDE

CAS: 5800-34-0

Formula: C₂₀H₂₁N₃O₆

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 399.403

Ref: 10-F500230

N-Glutaryl-L-phenylalanine p-nitroanilide

Controlled Product

CAS: 5800-34-0

Formula: C₂₀H₂₁N₃O₆

Color and Shape: Neat

Molecular weight: 399.397

Ref: TR-G597615

Glutaryl-Phe-pNA

CAS: 5800-34-0

Glutaryl-Phe-pNA is commonly used as a substrate to measure the activity of proteases, which are enzymes that cleave peptide bonds. The cleavage of the Glutaryl-Phe-pNA substrate by proteases releases a colored 4-nitroaniline product, which can be detected and quantified spectrophotometrically to measure protease activity.

Formula: C₂₀H₂₁N₃O₆

Purity: Min. 95%

Molecular weight: 399.4 g/mol

Ref: 3D-FG110727