CAS 58019-65-1

Nabazenil

Description:

Nabazenil, with the CAS number 58019-65-1, is a chemical compound that functions primarily as a benzodiazepine receptor antagonist. It is known for its role in pharmacology, particularly in the context of reversing the effects of benzodiazepines, which are commonly used for their sedative and anxiolytic properties. Nabazenil exhibits a high affinity for the GABA-A receptor, which is crucial for mediating the inhibitory effects of neurotransmitters in the central nervous system. The compound is characterized by its ability to displace benzodiazepines from their binding sites, thereby counteracting their sedative effects. This makes it a valuable agent in clinical settings, particularly in cases of benzodiazepine overdose or in situations where rapid reversal of sedation is required. Additionally, Nabazenil's pharmacokinetic properties, such as its absorption, distribution, metabolism, and excretion, contribute to its efficacy and safety profile, although specific details may vary based on formulation and administration routes. Overall, Nabazenil represents an important tool in the management of benzodiazepine-related complications.

Formula: C₃₅H₅₅NO₃

InChI: InChI=1S/C35H55NO3/c1-7-8-11-15-26(3)27(4)28-23-31(38-33(37)16-14-21-36-19-12-9-10-13-20-36)34-29-22-25(2)17-18-30(29)35(5,6)39-32(34)24-28/h23-27H,7-22H2,1-6H3

InChI key: InChIKey=DRVZFWZGQKGHQO-UHFFFAOYSA-N

SMILES: O(C(CCCN1CCCCCC1)=O)C2=C3C4=C(C(C)(C)OC3=CC(C(C(CCCCC)C)C)=C2)CCC(C)C4

Synonyms:

• 1H-Azepine-1-butanoic acid, hexahydro-, 3-(1,2-dimethylheptyl)-7,8,9,10-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran-1-yl ester
• Nabazenil
• 6H-Dibenzo[b,d]pyran, 1H-azepine-1-butanoic acid deriv.

Nabazenil

CAS: 58019-65-1

Nabazenil is a synthetic cannabinoid receptor agonist which has anticonvulsant properties.

Formula: C₃₅H₅₅NO₃

Color and Shape: Solid

Molecular weight: 537.82

Ref: TM-T69062