CAS 58066-85-6: Miltefosine

Description: Miltefosine is an organic compound primarily recognized for its use as an antiprotozoal medication, particularly in the treatment of leishmaniasis. It is classified as a phospholipid derivative and is characterized by its amphiphilic nature, which allows it to interact with both hydrophilic and hydrophobic environments. Miltefosine has a molecular formula that includes carbon, hydrogen, nitrogen, oxygen, and phosphorus, contributing to its complex structure. The substance is typically administered orally and is notable for its ability to disrupt cellular membranes and inhibit the growth of parasites. Its mechanism of action involves interference with lipid metabolism and apoptosis in the target organisms. Miltefosine is also associated with a range of side effects, including gastrointestinal disturbances and potential teratogenic effects, necessitating caution in its use, particularly in pregnant individuals. Additionally, it has been studied for potential applications beyond leishmaniasis, including its antiviral properties. Overall, Miltefosine represents a significant advancement in the pharmacological management of certain parasitic infections.

Formula: C₂₁H₄₆NO₄P

InChI: InChI=1S/C21H46NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-25-27(23,24)26-21-19-22(2,3)4/h5-21H2,1-4H3

InChI key: InChIKey=PQLXHQMOHUQAKB-UHFFFAOYSA-N

SMILES: O=P([O-])(OCCCCCCCCCCCCCCCC)OCC[N+](C)(C)C

Synonyms:

• 1-n-Hexadecylphosphorylcholine
• 2-(((Hexadecyloxy)Hydroxyphosphinyl)Oxy)-N,N,N-Trimethyl-Ethanaminiuhydrox
• 2-(((Hexadecyloxy)Hydroxyphosphinyl)Oxy)-N,N,N-Trimethylethanaminiumhydroxid
• Choline Hexadecyl Phosphate
• Choline phosphate, hexadecyl ester, hydroxide, inner salt
• Cholinephosphate,Hexadecylester,Hydroxide,Innersalt
• D 18506
• Ethanaminium, 2-[[(hexadecyloxy)hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt
• Fos-choline 16
• Hexadecyl 2-(Trimethylammonio)Ethyl Phosphate
• Hexadecylphosphorylcholine
• Impavido
• Miltefos
• Miltefosine
• Miltex
• NSC 605583
• n-Hexadecylphosphocholine
• n-Hexadecylphosphorylcholine
• Hexadecylphosphocholine

Miltefosine

CAS: 58066-85-6

• Formula: C₂₁H₄₆NO₄P
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 407.58

Miltefosine

CAS: 58066-85-6

Miltefosine (HePC), effective oral drug for both visceral and cutaneous leishmaniasis, in clinical trials worldwide.

• Formula: C₂₁H₄₆NO₄P
• Purity: 98% - 99.87%
• Color and Shape: White To Off-White Powder
• Molecular weight: 407.57

Miltefosine

CAS: 58066-85-6

• Formula: C₂₁H₄₆NO₄P
• Purity: ≥ 98.0% (anhydrous basis)
• Color and Shape: White or almost white powder
• Molecular weight: 407.57

Miltefosine

CAS: 58066-85-6

• Purity: 99.5%
• Molecular weight: 407.57g/mol

Miltefosine

CAS: 58066-85-6

• Formula: C₂₁H₄₆NO₄P
• Color and Shape: White To Off-White Solid
• Molecular weight: 407.58

Hexadecylphosphocholine

CAS: 58066-85-6

• Formula: H₂
• Color and Shape: white powder
• Molecular weight: 407.57g/mol

Miltefosine-d9

CAS: 58066-85-6

• Formula: C₂₁H₃₇D₉NO₄P
• Molecular weight: 416.63

Miltefosine

CAS: 58066-85-6

Applications A phospholipid drug with antineoplastic and antiprotozoal/antifungal properties, also acts as an Akt inhibitor, …

• Formula: C₂₁H₄₆NO₄P
• Color and Shape: Neat
• Molecular weight: 407.57

1-Hexadecylphosphocholine

CAS: 58066-85-6

M01856 - 1-Hexadecylphosphocholine

• Formula: C₂₁H₄₆NO₄P
• Purity: >99%
• Color and Shape: Solid
• Molecular weight: 407.57598876953125

1-Hexadecylphosphorylcholine

CAS: 58066-85-6

Treatment for leishmaniasis

• Formula: C₂₁H₄₆NO₄P
• Purity: Min 98%
• Color and Shape: White Powder
• Molecular weight: 407.57 g/mol

Hexadecylphosphocholine

CAS: 58066-85-6

Hexadecylphosphocholine, better known as miltefosine, belongs to the group of phospholipids. The long alkyl chain …

• Formula: C₂₁H₄₆NO₄P
• Molecular weight: 407.57 g/mol

Miltefosine-(d9)

CAS: 58066-85-6

• Formula: C₂₁H₃₇D₉NO₄P
• Color and Shape: Neat
• Molecular weight: 662.796