CAS 581-97-5

N-2-Naphthalenylacetamide

Description:

N-2-Naphthalenylacetamide, with the CAS number 581-97-5, is an organic compound characterized by its naphthalene moiety attached to an acetamide functional group. This compound typically appears as a white to off-white crystalline solid. It is known for its moderate solubility in organic solvents such as ethanol and acetone, while being less soluble in water. The presence of the naphthalene ring contributes to its aromatic properties, which can influence its reactivity and interactions with other substances. N-2-Naphthalenylacetamide may exhibit biological activity, making it of interest in pharmaceutical research, particularly in the development of potential therapeutic agents. Its melting point and boiling point can vary based on purity and environmental conditions. As with many organic compounds, handling should be done with care, considering potential health effects and environmental impact. Proper storage in a cool, dry place away from incompatible substances is recommended to maintain its stability and integrity.

Formula: C₁₂H₁₁NO

InChI: InChI=1/C12H11NO/c13-12(14)8-9-5-6-10-3-1-2-4-11(10)7-9/h1-7H,8H2,(H2,13,14)

InChI key: InChIKey=DIEOESIZLAHURK-UHFFFAOYSA-N

SMILES: N(C(C)=O)C1=CC2=C(C=C1)C=CC=C2

Synonyms:

• 2-(Naphthalen-2-Yl)Acetamide
• 2-Acetamidonaphthalene
• 2-Acetylaminonaphthalene
• Acetamide, N-2-naphthalenyl-
• Acetamide, N-2-naphthalenyl- (9CI)
• Acetamide, N-2-naphthyl-
• Ai3-16908
• Brn 2208926
• N-(2-Naphthyl)acetamide
• N-(naphthalen-2-yl)acetamide
• N-2-Naphthalenylacetamide
• N-Acetoxy-2-naphthylamine
• N-Acetyl-2-naphthylamine
• N-Acetyl-beta-naphthylamine
• N-Acetyl-β-naphthylamine
• Nsc 3104
• beta-Acetamidonaphthalide
• β-Acetonaphthalide
• N-2-Naphthylacetamide
• 4-12-00-03139 (Beilstein Handbook Reference)
• BETA-ACETAMIDONAPHTHALENE
• n-2-naphthyl-acetamid
• 2-Naphthylacetamide
• N-naphthalen-2-ylethanamide
• n-2-naphthalenyl-acetamid

Acetyl-β-naphthylamine

CAS: 581-97-5

Formula: C₁₂H₁₁NO

Purity: 99%

Color and Shape: Solid

Molecular weight: 185.2218

Ref: IN-DA003SOH

N-(Naphthalen-2-Yl)Acetamide

CAS: 581-97-5

N-(Naphthalen-2-Yl)Acetamide

Purity: 99%

Molecular weight: 185.22g/mol

Ref: 54-OR1030004

N-Acetyl-2-naphthylamine

Controlled Product

CAS: 581-97-5

Applications N-Acetyl-2-naphthylamine was used in the preparation of novel phenyl pyrazolone-substituted 1H-benzo[g]pyrazolo[3,4-b]quinoline-3-ylamine derivatives that exhibits antituberculosis and antibacterial activities.
References Parekh, N.M., et al.: Res. Chem. Inter. 30, 885 (2012); Parekh, N.M., et al.: Med. Chem., Res., 21, 4168 (2012);

Formula: C₁₂H₁₁NO

Color and Shape: Neat

Molecular weight: 185.22

Ref: TR-A186950

N-(Naphthalen-2-yl)acetamide

CAS: 581-97-5

N-(Naphthalen-2-yl)acetamide is a synthetic compound that has been shown to have anti-cancer and anti-inflammatory properties. It is a prodrug of N-(naphthalen-2-yl)acetamide, the active form. The prodrug is hydrolyzed in vivo to the active form by the action of hydrochloric acid in mammalian cells. The prodrug also binds to amines and oligodeoxynucleotides and inhibits their synthesis. In addition, it inhibits calcium pantothenate, which is an essential cofactor for DNA synthesis. N-(Naphthalen-2-yl)acetamide also has been shown to inhibit tumor growth in animal models by blocking DNA synthesis and cell proliferation. The drug is metabolized into chloride ions that are toxic to cancer cells but not normal cells. The optimum pH for this reaction is 7.5.

Formula: C₁₂H₁₁NO

Purity: Min. 95%

Molecular weight: 185.22 g/mol

Ref: 3D-AAA58197