CAS 58131-57-0

7-(4-methylpiperazin-1-yl)-4-nitro-2,1,3-benzoxadiazole 1-oxide

Description:

7-(4-Methylpiperazin-1-yl)-4-nitro-2,1,3-benzoxadiazole 1-oxide, with the CAS number 58131-57-0, is a chemical compound characterized by its unique structure, which includes a benzoxadiazole core substituted with a nitro group and a piperazine moiety. This compound typically exhibits properties such as moderate solubility in organic solvents and potential stability under standard laboratory conditions. The presence of the nitro group suggests that it may participate in electrophilic reactions, while the piperazine ring can contribute to its biological activity, possibly influencing its interaction with biological targets. Additionally, the 1-oxide functional group may impart specific reactivity or stability characteristics. This compound is of interest in various fields, including medicinal chemistry and materials science, due to its potential applications in drug development and as a fluorescent probe. Safety and handling precautions should be observed, as with many nitro-containing compounds, due to potential toxicity and environmental concerns.

Formula: C₁₁H₁₃N₅O₄

InChI: InChI=1/C11H13N5O4/c1-13-4-6-14(7-5-13)9-3-2-8(15(17)18)10-11(9)16(19)20-12-10/h2-3H,4-7H2,1H3

InChI key: InChIKey=MWFZDJLPWDCQIL-UHFFFAOYSA-N

SMILES: CN1CCN(CC1)c1ccc(c2c1n(=O)on2)N(=O)=O

Synonyms:

• 2,1,3-Benzoxadiazole, 4-(4-methyl-1-piperazinyl)-7-nitro-, 3-oxide
• 2,1,3-Benzoxadiazole, 7-(4-Methyl-1-Piperazinyl)-4-Nitro-, 1-Oxide
• 4-(4-Methyl-1-piperazinyl)-7-nitro-2,1,3-benzoxadiazole 3-oxide
• Benzofurazan, 4-(4-methyl-1-piperazinyl)-7-nitro-, 3-oxide
• NSC 179940
• NSC 207895
• Xi-006
• 7-(4-Methylpiperazin-1-yl)-4-nitro-2,1,3-benzoxadiazole 1-oxide

NSC 207895

CAS: 58131-57-0

Formula: C₁₁H₁₃N₅O₄

Purity: 99%

Color and Shape: Solid

Molecular weight: 279.2520

Ref: IN-DA00EFGD

XI-006

CAS: 58131-57-0

XI-006

Purity: ≥98%

Molecular weight: 279.25g/mol

Ref: 54-BUP12217

XI-006

CAS: 58131-57-0

NSC-207895 (XI-006) suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and regulates MDM2, an E3 ligase.

Formula: C₁₁H₁₃N₅O₄

Purity: 99.51%

Color and Shape: Solid

Molecular weight: 279.25

Ref: TM-T6610

NSC 207895

CAS: 58131-57-0

NSC 207895 is a small molecule that inhibits the activity of ubiquitin ligases. It has been shown to inhibit tumor growth in animal models, as well as decrease the viability of cancer cells. NSC 207895 has also been shown to have anticancer activity against human breast cancer cells and to reduce the size of xenograft tumors in mice. NSC 207895 is a biocompatible polymer with no known toxicity in animals. The mechanism of action for NSC 207895 is unclear, but it may be due to inhibition of epidermal growth factor receptor (EGFR) signaling or interference with cell nuclei.

Formula: C₁₁H₁₃N₅O₄

Purity: Min. 95%

Molecular weight: 279.25 g/mol

Ref: 3D-ICA13157