CAS 58151-27-2

Toyocamycin monohydrate

CAS: 58151-27-2

Toyocamycin is a macrolide antibiotic that inhibits protein synthesis by binding to the 50S ribosomal subunit. Toyocamycin monohydrate (TM) has been shown to have significant cytotoxicity against HL-60 cells, which may be due to its ability to inhibit mitochondrial membrane potential and induce apoptosis. The drug also has inhibitory properties against wild-type strains of bacteria, such as diastatochromogenes, and is active against high-resistant strains of bacteria, such as E. coli. Toyocamycin monohydrate has been shown to inhibit transcriptional regulation in hl-60 cells and k562 cells by binding to RNA polymerase II and blocking RNA synthesis.

Formula: C₁₂H₁₃N₅O₄•H₂O

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 309.28 g/mol

Ref: 3D-NT44985