CAS 58151-90-9

1-(5-O-Benzoyl-β-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide

Description:

1-(5-O-Benzoyl-β-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide is a chemical compound characterized by its unique structural features, which include a triazole ring and a ribofuranosyl moiety. This compound is notable for its potential biological activity, particularly in the realm of medicinal chemistry, where triazole derivatives are often explored for their antifungal and antiviral properties. The presence of the benzoyl group enhances its lipophilicity, potentially improving its ability to penetrate biological membranes. The carboxamide functional group contributes to its solubility and may play a role in hydrogen bonding interactions, influencing its pharmacokinetic properties. Additionally, the ribofuranosyl component suggests that this compound may interact with nucleic acids or enzymes involved in nucleic acid metabolism. Overall, the combination of these structural elements positions this compound as a candidate for further research in drug development, particularly in targeting specific biological pathways or diseases.

Formula: C₁₅H₁₆N₄O₆

InChI: InChI=1S/C15H16N4O6/c16-12(22)13-17-7-19(18-13)14-11(21)10(20)9(25-14)6-24-15(23)8-4-2-1-3-5-8/h1-5,7,9-11,14,20-21H,6H2,(H2,16,22)/t9-,10-,11-,14-/m1/s1

InChI key: InChIKey=DFCVOGPUXOBQKK-ZHSDAYTOSA-N

SMILES: O[C@H]1[C@@H](O[C@H](COC(=O)C2=CC=CC=C2)[C@H]1O)N3N=C(C(N)=O)N=C3

Synonyms:

• 1H-1,2,4-Triazole-3-carboxamide, 1-(5-O-benzoyl-β-D-ribofuranosyl)-
• 1-(5-O-Benzoyl-β-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide

Ribavirin Impurity E

CAS: 58151-90-9

Formula: C₁₅H₁₆N₄O₆

Color and Shape: White To Off-White Solid

Molecular weight: 348.32

Ref: 4Z-R-047

1-(5-O-Benzoyl-β-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide (5'-O-Benzoylribavirin)

Controlled Product

CAS: 58151-90-9

Formula: C₁₅H₁₆N₄O₆

Color and Shape: Neat

Molecular weight: 348.31

Ref: 86-MM0542.05

5’-O-Benzoyl Ribavirin

Controlled Product

CAS: 58151-90-9

Applications 5’-O-Benzoyl Ribavirin is an impurity of Ribavirin (R414475). Ribavirin impurity E.
References Zakharieva., et al.: Bioorganic. Medicinal. Chem., 1994, 4, 2831 (1994), Reichard., et al.: The Lancet, 351, 83 (1998),

Formula: C₁₅H₁₆N₄O₆

Color and Shape: Neat

Molecular weight: 348.31

Ref: TR-B209580

Ribavirin Impurity E

CAS: 58151-90-9

Formula: C₁₅H₁₆N₄O₆

Molecular weight: 348.32

Ref: ST-EA-CP-R81013