CAS 581772-29-4

(4R,6R)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid

Description:

The chemical substance with the name "(4R,6R)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid" and CAS number "581772-29-4" is a complex organic compound characterized by its multi-ring structure and various functional groups. It features a pyrrole ring, which is known for its aromatic properties, and incorporates a dioxane moiety, contributing to its potential solubility and reactivity. The presence of a fluorophenyl group suggests enhanced biological activity or lipophilicity, while the phenylamino carbonyl group may indicate potential interactions in biological systems. The stereochemistry indicated by the (4R,6R) configuration suggests specific spatial arrangements that can influence the compound's biological activity and pharmacokinetics. Overall, this compound is likely to exhibit unique chemical properties and potential applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific biological pathways.

Formula: C₃₆H₃₉FN₂O₅

InChI: InChI=1S/C36H39FN2O5/c1-23(2)33-32(35(42)38-27-13-9-6-10-14-27)31(24-11-7-5-8-12-24)34(25-15-17-26(37)18-16-25)39(33)20-19-28-21-29(22-30(40)41)44-36(3,4)43-28/h5-18,23,28-29H,19-22H2,1-4H3,(H,38,42)(H,40,41)/t28-,29-/m1/s1

InChI key: InChIKey=YFMKJVDVNPLQFO-FQLXRVMXSA-N

SMILES: C(NC1=CC=CC=C1)(=O)C=2C(=C(N(CC[C@@H]3C[C@H](CC(O)=O)OC(C)(C)O3)C2C(C)C)C4=CC=C(F)C=C4)C5=CC=CC=C5

Synonyms:

• 2-[(4R,6R)-6-[2-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetic acid
• 1,3-Dioxane-4-acetic acid, 6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-, (4R,6R)-
• Atorvastatin acetonide
• (4R,6R)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid
• Lipitor acetonide

Atorvastatin EP Impurity P

CAS: 581772-29-4

Formula: C₃₆H₃₉FN₂O₅

Color and Shape: White To Off-White Solid

Molecular weight: 598.72

Ref: 4Z-A-1210

Atorvastatin acetonide

CAS: 581772-29-4

Atorvastatin acetonide

Purity: 95%

Molecular weight: 598.71g/mol

Ref: 54-PC109446

Atorvastatin Acetonide

CAS: 581772-29-4

Color and Shape: Neat

Ref: 86-MM0400.41

Atorvastatin Acetonide

CAS: 581772-29-4

Applications Protected Atorvastatin.

Formula: C₃₆H₃₉FN₂O₅

Color and Shape: Off-White To Light Yellow

Molecular weight: 598.70

Ref: TR-A791690

Atorvastatin acetonide

CAS: 581772-29-4

Atorvastatin acetonide, an impurity in Atorvastatin, lowers blood lipids; from patent WO2011131605A1.

Formula: C₃₆H₃₉FN₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 598.7

Ref: TM-T10401

Atorvastatin acetonide

CAS: 581772-29-4

Atorvastatin acetonide is a statin drug that inhibits the synthesis of cholesterol by the liver. It is used to lower high cholesterol and triglycerides, as well as to reduce the risk of cardiovascular disease. Atorvastatin acetonide is a prodrug that is hydrolyzed in vivo to atorvastatin. Atorvastatin acetonide can be analyzed by HPLC with UV detection or by reversed-phase HPLC with fluorescence detection. The flow rate for this analysis is 0.5 mL/min and it takes about 20 min for analysis time. In order to monitor reaction progress, a calibration curve should be used for calibration and reaction monitoring. This product has linearity with recoveries of greater than 75%.

Formula: C₃₆H₃₉FN₂O₅

Purity: Min. 95%

Molecular weight: 598.7 g/mol

Ref: 3D-FA18011

Atorvastatin EP Impurity P

CAS: 581772-29-4

Formula: C₃₆H₃₉FN₂O₅

Molecular weight: 598.72

Ref: ST-EA-CP-A32038