CAS 582-36-5

Thiazolium, 3-[(1,6-dihydro-2-methyl-6-oxo-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-, chloride (1:1)

Description:

Thiazolium, 3-[(1,6-dihydro-2-methyl-6-oxo-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-, chloride (1:1), with CAS number 582-36-5, is a chemical compound characterized by its thiazolium ring structure, which is a five-membered heterocyclic ring containing sulfur and nitrogen. This compound features a pyrimidinyl moiety, contributing to its biological activity and potential pharmacological properties. The presence of hydroxyl and methyl groups enhances its solubility and reactivity. As a chloride salt, it exists in a stable ionic form, which can influence its interaction with biological systems. Thiazolium compounds are often studied for their roles in various biochemical processes, including enzyme catalysis and as intermediates in organic synthesis. The specific structural features of this compound suggest potential applications in medicinal chemistry, particularly in the development of therapeutics targeting specific biological pathways. Its unique combination of functional groups may also impart interesting properties, such as antioxidant or antimicrobial activity, warranting further investigation in both synthetic and biological contexts.

Formula: C₁₂H₁₆ClN₃O₂S

InChI: InChI=1/C12H15N3O2S.ClH/c1-8-11(3-4-16)18-7-15(8)6-10-5-13-9(2)14-12(10)17;/h5,7,16H,3-4,6H2,1-2H3;1H

InChI key: InChIKey=RNUAEUWXRHCGKX-UHFFFAOYSA-N

SMILES: C([N+]=1C(C)=C(CCO)SC1)C=2C(=O)NC(C)=NC2.[Cl-]

Synonyms:

• 3-[(1,4-Dihydro-2-methyl-4-oxo-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium Chloride
• 5-(2-Hydroxyethyl)-3-[(4-hydroxy-2-methyl-5-pyrimidinyl)methyl]-4-methylthiazolium Chloride
• 5-(2-Hydroxyethyl)-3-[(4-hydroxy-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium chloride
• 5-(2-Hydroxyethyl)-4-Methyl-3-[(2-Methyl-6-Oxo-1,6-Dihydropyrimidin-5-Yl)Methyl]-1,3-Thiazol-3-Ium Chloride
• 582-36-5
• Hydroxythiamine
• Oxythiamine chloride
• Thiazolium, 3-[(1,4-dihydro-2-methyl-4-oxo-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-, chloride
• Thiazolium, 3-[(1,6-dihydro-2-methyl-6-oxo-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-, chloride (1:1)
• Thiamine 4-Hydroxy
• 5-[[5-(2-hydroxyethyl)-4-methyl-thiazol-3-ium-3-yl]methyl]-2-methyl-1H-pyrimidin-6-one chloride
• 5-(2-hydroxyethyl)-3-(4-hydroxy-2-methylpyrimidin-5-ylmethyl)-4-methylthiazolium chloride

Oxythiamine chloride

CAS: 582-36-5

Oxythiamine chloride is a compound that binds to DNA in the nucleus of cells. It has been shown to inhibit cell growth and induce apoptosis by binding to a number of cellular molecules, including hydrogen bonding interactions with enzymes. Oxythiamine chloride also inhibits energy metabolism by inhibiting mitochondrial respiration and mitochondrial ATP production, and is toxic to cells. This drug has potent inducers, such as cell factor, which are necessary for the production of new cells. It also inhibits thiamine-dependent enzymes, such as pyruvate dehydrogenase kinase (PDK) and pyruvate dehydrogenase (PDH). The wild-type strain of Escherichia coli was used for these studies.

Formula: C₁₂H₁₅N₃O₂S·HCl

Purity: Min. 95%

Color and Shape: White to off-white solid.

Molecular weight: 301.79 g/mol

Ref: 3D-FO29785