CAS 58261-91-9

Mefenidil

Description:

Mefenidil is a chemical compound classified as a non-steroidal anti-inflammatory drug (NSAID) primarily used for its analgesic and anti-inflammatory properties. It is characterized by its ability to inhibit cyclooxygenase enzymes, which play a crucial role in the synthesis of prostaglandins, thereby reducing pain and inflammation. Mefenidil is typically administered in oral form and is known for its moderate potency. The compound has a relatively low solubility in water, which can affect its bioavailability and absorption in the body. Its chemical structure includes a phenyl group and a carboxylic acid moiety, contributing to its pharmacological activity. Mefenidil is often utilized in the treatment of various conditions, including musculoskeletal disorders and pain management. However, like other NSAIDs, it may be associated with side effects such as gastrointestinal discomfort and cardiovascular risks, necessitating careful consideration of its use in patients with pre-existing conditions. Overall, Mefenidil represents a valuable option in the realm of pain relief and inflammation control.

Formula: C₁₂H₁₁N₃

InChI: InChI=1S/C12H11N3/c1-9-11(7-8-13)15-12(14-9)10-5-3-2-4-6-10/h2-6H,7H2,1H3,(H,14,15)

InChI key: InChIKey=OTRQRKIYHATFKM-UHFFFAOYSA-N

SMILES: C(C#N)C=1NC(=NC1C)C2=CC=CC=C2

Synonyms:

• UNII-74WY8560J7
• 1H-Imidazole-5-acetonitrile, 4-methyl-2-phenyl-
• 4-Methyl-2-phenyl-1H-imidazole-5-acetonitrile
• Mefenidilum
• 5-Mehylt-2-phenyl-4-imidazolacetonitril
• 1H-Imidazole-4-acetonitrile, 5-methyl-2-phenyl-
• Mefenidilum [Latin]
• Mefenidil [USAN:INN]
• Mefenidil
• (5-methyl-2-phenyl-1H-imidazol-4-yl)acetonitrile
• McN 2378
• 5-Methyl-2-phenylimidazole-4-acetonitrile
• 1H-Imidazole-4-acetonitrile, 5-methyl-2-phenyl-

Mefenidil

CAS: 58261-91-9

Mefenidil

Purity: ≥98%

Molecular weight: 197.24g/mol

Ref: 54-BUP07267

Mefenidil

CAS: 58261-91-9

Formula: C₁₂H₁₁N₃

Molecular weight: 197.24

Ref: 4Z-M-273001

Mefenidil

CAS: 58261-91-9

Mefenidil (McN-2378), a selective cerebral vasodilator, was shown to increase CBF in healthy brains without stimulating O2 uptake in a dog anesthesia model.

Formula: C₁₂H₁₁N₃

Purity: 98.27%

Color and Shape: Solid

Molecular weight: 197.24

Ref: TM-T33272