CAS 58288-50-9

Hydroxocobalamin hydrochloride

Description:

Hydroxocobalamin hydrochloride is a form of vitamin B12, specifically a cobalamin compound, characterized by its red color due to the presence of cobalt. It is a water-soluble vitamin that plays a crucial role in various biological processes, including DNA synthesis, red blood cell formation, and neurological function. Hydroxocobalamin is often used in clinical settings as a treatment for vitamin B12 deficiency and as an antidote for cyanide poisoning due to its ability to bind cyanide ions, forming a non-toxic complex. The compound is typically administered via intramuscular or intravenous routes, and its pharmacokinetics involve storage in the liver, where it can be released as needed. Hydroxocobalamin hydrochloride is generally well-tolerated, with side effects being rare but may include allergic reactions or injection site reactions. Its stability and efficacy make it a valuable therapeutic agent in both nutritional supplementation and emergency medicine.

Formula: C₆₂H₈₉CoN₁₃O₁₅P·xClH

InChI: InChI=1S/C62H90N13O14P.ClH.Co.H2O/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H;;1H2/q;;+3;/p-3

InChI key: InChIKey=KEHNCSYXYMMUCO-UHFFFAOYSA-K

SMILES: [OH-][Co+3]1234[N]=5C6(C)C7[N-]1C(C(C)(C7CC(N)=O)CCC(=O)NCC(C)OP(=O)([O-])OC8C(O)C(N9C=[N]2C=%10C9=CC(C)=C(C)C%10)OC8CO)=C(C)C%11=[N]3C(=CC%12=[N]4C(=C(C)C5C(CCC(N)=O)C6(CC(N)=O)C)C(CC(N)=O)(C)C%12CCC(N)=O)C(C)(C)C%11CCC(N)=O.Cl

Synonyms:

• Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3′-ester with (5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole-κN³), hydrochloride
• Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3′-ester with (5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole-κN³), hydrochloride (1:?)
• Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono(inner salt), 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole, hydrochloride
• Hydroxocobalamin Chloride
• Hydroxocobalamine Hydrochloride
• Vitamin B12A Hydrochloride
• hydroxocobalamin HCl
• hydroxy-[(1R,2R,3R,4Z,7S,9Z,12S,13S,14Z,17S,18S,19R)-2,13,18-tris(2-amino-2-oxo-ethyl)-7,12,17-tris(3-amino-3-oxo-propyl)-3-[3-[[(2R)-2-[[(2R,3S,4R,5S)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl]oxy-oxido-phosphoryl]oxypropyl]amino]-3-oxo-propyl]-3,5,8,8,13,15,18,19-octamethyl-2,7,12,17-tetrahydro-1H-corrin-21-yl]cobalt(1+) hydrochloride
• Hydroxocobalamin hydrochloride
• Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3′-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3), hydrochloride
• Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3′-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3), hydrochloride (1:?)

HYDROXOCOBALAMIN CRS

CAS: 58288-50-9

HYDROXOCOBALAMIN CRS

Ref: 41-H1428000

Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3'-esterwith (5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole-kN3),hydrochloride

CAS: 58288-50-9

Formula: C₆₂H₉₀ClCoN₁₃O₁₅P

Purity: 98%

Color and Shape: Solid

Molecular weight: 1382.8161

Ref: IN-DA00E91P

Vitamin B12a hydrochloride

CAS: 58288-50-9

Vitamin B12a monohydrochloride (Hydroxocobalamin) is an essential water-soluble vitamin.a cyanide detoxifier and nutritional supplement, injection, inhalation.

Formula: C₆₂H₈₉CoN₁₃O₁₅P·xHCl

Color and Shape: Solid

Ref: TM-T204095

Hydroxocobalamin hydrochloride

CAS: 58288-50-9

Formula: C₆₂H₈₉CoN₁₃O₁₅P·HCl

Purity: 96.0 - 102.0 %

Color and Shape: Off-white to dark red or brown crystalline powder

Molecular weight: 1382.82

Ref: 7W-GE2054

Hydroxocobalamin Xhydrochloride

CAS: 58288-50-9

Hydroxocobalamin Xhydrochloride

Purity: 98%

Molecular weight: 1,382.82g/mol

Ref: 54-OR1013543

Vitamin B12a

CAS: 58288-50-9

Formula: C₆₂H₉₀ClCoN₁₃O₁₅P

Molecular weight: 1382.82

Ref: 7W-GL8242

Hydroxocobalamin HCl

CAS: 58288-50-9

Hydroxocobalamin HCl is a vitamin that is required for the formation of coenzyme B12. It is used to treat megaloblastic anemia, pernicious anemia, and other conditions in which vitamin B12 is deficient. Hydroxocobalamin HCl also has been shown to have physiological effects, including the inhibition of enzyme activities such as nitrite reductase and sephadex g-100. This drug binds to a number of enzymes, including group P2 enzymes (e.g., nitrate reductase) and thermolytic enzymes (e.g., hydroxylases). Hydroxocobalamin HCl has a redox potential that allows it to act as a hydrogen donor in reactions with electron acceptors such as nitrite ion or oxygen. The mechanism of action of hydroxocobalamin includes its ability to reduce intramolecular hydrogen molecules, which can be transferred to other molecules in the reaction system such as

Formula: C₆₂H₈₉CoN₁₃O₁₅P•(HCl)x

Purity: Min. 90 Area-%

Color and Shape: Powder

Molecular weight: 1,346.35 g/mol

Ref: 3D-FH45888

Hydroxocobalamin Hydrochloride (>85%)

CAS: 58288-50-9

Applications Hydroxocobalamin Hydrochloride acts as a spin trap for radical polymerization in water when reduced with ascorbic acid.
References Ng, Y., et al.: Macromol. Res., 20, 473-476 (2012)

Formula: C₆₂H₈₉CoN₁₃O₁₅P·ClH

Color and Shape: Neat

Molecular weight: 1382.82

Ref: TR-H862823

Cyanocobalamin EP Impurity H Chloride (Hydroxocobalamin Chloride)

CAS: 58288-50-9

Formula: C₆₂H₈₉CoN₁₃O₁₅P·HCl

Molecular weight: 1382.82 36.46

Ref: 4Z-C-165020