CAS 583-08-4

Nicotinuric acid

Description:

Nicotinuric acid, with the CAS number 583-08-4, is a chemical compound that is a derivative of nicotinic acid (niacin) and is characterized by its carboxylic acid functional group. It appears as a white to off-white crystalline solid and is soluble in water, which facilitates its biological activity. This compound is known for its role in the metabolism of nicotine and has been studied for its potential effects on nicotine addiction and its influence on the central nervous system. Nicotinuric acid is also recognized for its antioxidant properties, which may contribute to its physiological effects. In terms of its chemical structure, it contains a pyridine ring, which is typical of compounds related to nicotine, and a carboxyl group that imparts acidic characteristics. Its synthesis typically involves the reaction of nicotinic acid with various reagents, and it can be analyzed using techniques such as chromatography and spectroscopy. Overall, nicotinuric acid is of interest in both pharmacological research and the study of nicotine's effects on human health.

Formula: C₈H₈N₂O₃

InChI: InChI=1/C8H8N2O3/c11-7(12)5-10-8(13)6-2-1-3-9-4-6/h1-4H,5H2,(H,10,13)(H,11,12)

InChI key: InChIKey=ZBSGKPYXQINNGF-UHFFFAOYSA-N

SMILES: C(NCC(O)=O)(=O)C=1C=CC=NC1

Synonyms:

• (Nicotinoylamino)acetic acid
• 2-(Nicotinamido)aceticacid
• 2-(Nicotinylamino)acetic acid
• 2-(Pyridin-3-ylformamido)acetic acid
• 2-(Pyridine-3-carbonylamino)acetic acid
• 2-[(Pyridin-3-yl)formamido]acetic acid
• Glycine, N-(3-pyridinylcarbonyl)-
• Glycine, N-nicotinoyl-
• N-(3-Pyridinylcarbonyl)glycine
• N-(pyridin-3-ylcarbonyl)glycine
• NSC 71273
• Nicotinoyl-glycine
• Nicotinoylglycine
• Nicotinylglycine
• [(Pyridin-3-ylcarbonyl)amino]acetic acid
• NICOTINURIC ACID
• N-Nicotinuricacid
• 2-[(3-Pyridylcarbonyl)amino]acetic acid
• Nicotinuric
• Nic-Gly-OH
• NICOTINOYL-GLY-OH
• N-NicotinuricAcid~99%
• NICOTINICAMIDO ACETIC ACID
• N-NICOTINOYLGLYCINE

N-Nicotinoylglycine

CAS: 583-08-4

Formula: C₈H₈N₂O₃

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 180.16

Ref: 3B-N0092

Nicotinuric acid, 98+%

CAS: 583-08-4

Measurement of NUA levels in urine is used to indicate possible elevated nicotinamide adenine dinucleotide (NAD) catabolism. NUA may be used as a reference (standard curve) in analysis of NAD and NUA catabolism. It is an antiproliferative. This Thermo Scientific Chemicals brand product was original

Formula: C₈H₈N₂O₃

Purity: 98+%

Molecular weight: 180.16

Ref: 02-J62215

NICOTINOYL-GLYCINE

CAS: 583-08-4

Formula: C₈H₈N₂O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 180.1607

Ref: IN-DA003F3X

Nicotinuric acid

CAS: 583-08-4

Formula: C₈H₈N₂O₃

Purity: (HPLC) ≥ 97.0%

Color and Shape: White to off-white powder

Molecular weight: 180.16

Ref: 7W-GL4312

[(Pyridin-3-ylcarbonyl)amino]acetic acid

CAS: 583-08-4

[(Pyridin-3-ylcarbonyl)amino]acetic acid

Purity: 99%

Molecular weight: 180.16072g/mol

Ref: 54-OR14774

Nicotinuric acid

CAS: 583-08-4

Nicotinuric acid

Purity: ≥98%

Molecular weight: 180.16g/mol

Ref: 54-BUP14559

Nicotinuric Acid

Controlled Product

CAS: 583-08-4

Formula: C₈H₈N₂O₃

Color and Shape: Neat

Molecular weight: 180.16

Ref: 86-MM0553.13

Nicotinuric acid

CAS: 583-08-4

Nicotinuric acid: a minor acyl glycine metabolite of fatty acids, synthesized by glycine N-acyltransferase.

Formula: C₈H₈N₂O₃

Purity: 99.58%

Color and Shape: Solid

Molecular weight: 180.16

Ref: TM-T5228

Nicotinuric Acid

Controlled Product

CAS: 583-08-4

Applications A Niacin analog for therapeutic use. Antiproliferative.
References Carlson, L., et al.: Life Sci., et al.: 3, 867 (1964), Felsted, R., et al.: J. Biol. Chem., 242, 1274 (1967), Mrochek, J., et al.: Clin. Chem., 22, 1821 (1976), Ding, R., et al.: Clin. Pharmacol. Ther., 46, 642 (1989), Bottorff, M., et al.: Am. J. Cardiol., 97, 27 (2006),

Formula: C₈H₈N₂O₃

Color and Shape: Neat

Molecular weight: 180.16

Ref: TR-N433500

2-(Nicotinamido)acetic acid

CAS: 583-08-4

Formula: C₈H₈N₂O₃

Purity: 97%

Color and Shape: Solid, White to almost white powder

Molecular weight: 180.163

Ref: 10-F239820

Nicotinuric acid

CAS: 583-08-4

Nicotinuric acid is an endogenous metabolite of nicotinic acid, which is a cofactor for the enzyme that catalyzes the conversion of phosphoenolpyruvate to pyruvate. Nicotinuric acid has been shown to be a potential biomarker for human pharmacokinetics. It has been shown to be involved in energy metabolism and may play a role in the pathogenesis of atherosclerotic cardiovascular disease. Nicotinuric acid is also a product of the enzymatic degradation of pyrrolidinecarboxylic acid, which is found in papillary muscle cells and penicillin-binding protein. The formation of nicotinuric acid can be inhibited by nicotinic acid, pyrazinoic acid, or by inhibitors of lc-ms/ms method.

Formula: C₈H₈N₂O₃

Purity: Min. 95%

Molecular weight: 180.16 g/mol

Ref: 3D-FN26212

Nicotinuric Acid

CAS: 583-08-4

Formula: C₈H₈N₂O₃

Molecular weight: 180.16

Ref: ST-EA-CP-N8021

Nicotinuric Acid

CAS: 583-08-4

Color and Shape: Neat

Ref: 61-FOR0553.13