CAS 58316-41-9

Saikosaponin B2

Description:

Saikosaponin B2 is a triterpenoid saponin primarily derived from the roots of the plant Bupleurum falcatum, commonly known for its use in traditional medicine. This compound is characterized by its complex structure, which includes a steroid-like backbone and sugar moieties that contribute to its biological activity. Saikosaponin B2 exhibits various pharmacological properties, including anti-inflammatory, hepatoprotective, and immunomodulatory effects. It has been studied for its potential therapeutic applications in conditions such as liver diseases and cancer. The compound is typically soluble in organic solvents and exhibits low solubility in water, which can influence its bioavailability and efficacy. Additionally, Saikosaponin B2 is known to interact with various biological targets, making it a subject of interest in pharmacological research. Its safety profile and potential side effects are still under investigation, emphasizing the need for further studies to fully understand its therapeutic potential and mechanisms of action.

Formula: C₄₂H₆₈O₁₃

InChI: InChI=1S/C42H68O13/c1-21-29(47)34(55-35-32(50)31(49)30(48)24(18-43)53-35)33(51)36(52-21)54-28-11-12-38(4)25(39(28,5)19-44)10-13-40(6)26(38)9-8-22-23-16-37(2,3)14-15-42(23,20-45)27(46)17-41(22,40)7/h8-9,21,24-36,43-51H,10-20H2,1-7H3/t21-,24-,25-,26-,27-,28+,29+,30-,31+,32-,33-,34+,35+,36+,38+,39+,40-,41-,42-/m1/s1

InChI key: InChIKey=WRYJYFCCMSVEPQ-ORAXXRKOSA-N

SMILES: C[C@]12C(=C3[C@@](CO)([C@H](O)C1)CCC(C)(C)C3)C=C[C@]4([C@@]2(C)CC[C@@]5([C@]4(C)CC[C@H](O[C@H]6[C@H](O)[C@@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@@H](O)[C@@H](C)O6)[C@]5(CO)C)[H])[H]

Synonyms:

• (3b,4a,16a)-16,23,28-Trihydroxyoleana-11,13(18)-dien-3-yl-6-deoxy-3-O-beta-D-glucopyranosyl-beta-D-galactopyranoside
• (3beta,16alpha)-16,23,28-trihydroxyoleana-11,13(18)-dien-3-yl 6-deoxy-3-O-beta-D-glucopyranosyl-beta-D-galactopyranoside
• (3β,4α,16α)-16,23,28-Trihydroxyoleana-11,13(18)-dien-3-yl 6-deoxy-3-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-galactopyranoside
• Saikosaponin B₂
• β-<span class="text-smallcaps">D</smallcap>-Galactopyranoside, (3β,4α,16α)-16,23,28-trihydroxyoleana-11,13(18)-dien-3-yl 6-deoxy-3-O-β-<smallcap>D</span>-glucopyranosyl-
• Saikosaponin B2
• (3β,4α,16α)-16,23,28-Trihydroxyoleana-11,13(18)-dien-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-β-D-galactopyranoside
• β-D-Galactopyranoside, (3β,4α,16α)-16,23,28-trihydroxyoleana-11,13(18)-dien-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-

Saikosaponin B2

CAS: 58316-41-9

Formula: C₄₂H₆₈O₁₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 780.9815

Ref: IN-DA00E9OC

Saikosaponin B2

CAS: 58316-41-9

Saikosaponin B2

Purity: ≥98%

Molecular weight: 780.98g/mol

Ref: 54-BUP02886

Saikosaponin B2

CAS: 58316-41-9

Ref: 7W-GC4522

Saikosaponin B2

CAS: 58316-41-9

Saikosaponin B2(SSb2) is an efficient inhibitor of early entry, including neutralization of virus particles, preventing viral attachment, and inhibiting viral entry/fusion, SSb2 may be of value for development as an antagonist of entry and could be explored as prophylactic treatment during the course of liver transplantation.

Formula: C₄₂H₆₈O₁₃

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 780.993

Ref: BP-BP1240

Saikosaponin B2

CAS: 58316-41-9

Formula: C₄₂H₆₈O₁₃

Purity: >95.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 780.99

Ref: 3B-A3610

Saikosaponin B2

CAS: 58316-41-9

Saikosaponin B2 inhibits HCV, blocks viral binding to hepatoma cells, and induces melanoma differentiation, enhancing tyrosinase and melanogenesis.

Formula: C₄₂H₆₈O₁₃

Purity: 99.18% - 99.59%

Color and Shape: Solid

Molecular weight: 780.98

Ref: TM-T3810

Saikosaponin b2

CAS: 58316-41-9

Natural glycoside

Formula: C₄₂H₆₈O₁₃

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 781

Ref: 5G-83539

Saikosaponin B2

CAS: 58316-41-9

Saikosaponin B2 is a naturally occurring triterpenoid saponin, which is a secondary metabolite primarily sourced from the roots of Bupleurum species. These plants are widely used in traditional Chinese medicine, valued for their diverse pharmacological activities. The mode of action of Saikosaponin B2 involves modulation of inflammatory pathways, specifically through the inhibition of pro-inflammatory cytokines and reduction of oxidative stress. It also exhibits potential in modulating immune responses and possesses hepatoprotective effects.

Formula: C₄₂H₆₈O₁₃

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 780.98 g/mol

Ref: 3D-OS09507