CAS 58331-17-2

Narasin sodium salt

Description:

Narasin sodium salt is a polyether ionophore antibiotic primarily used as a feed additive in livestock to promote growth and prevent coccidiosis, a parasitic disease affecting the intestinal tract of animals. It is derived from the fermentation of specific strains of Streptomyces bacteria. The compound exhibits a unique ability to form complexes with cations, particularly monovalent ions like sodium and potassium, which disrupts ion transport across cell membranes, ultimately affecting cellular metabolism and growth of certain pathogens. Narasin is characterized by its relatively low solubility in water, which influences its bioavailability and efficacy in animal feed formulations. It is typically administered in small quantities, and its use is regulated to ensure safety and minimize the risk of antibiotic resistance. Additionally, narasin has a specific mode of action that targets the electron transport chain in susceptible organisms, making it effective against a range of protozoa and some Gram-positive bacteria. As with all veterinary pharmaceuticals, proper handling and adherence to recommended dosages are essential to ensure animal health and food safety.

Formula: C₄₃H₇₁O₁₁Na

InChI: InChI=1S/C43H72O11.Na/c1-12-30(35(46)27(8)34(45)28(9)36-23(4)21-24(5)37(51-36)31(13-2)39(47)48)38-25(6)22-26(7)42(52-38)18-15-32(44)43(54-42)20-19-40(11,53-43)33-16-17-41(49,14-3)29(10)50-33;/h15,18,23-34,36-38,44-45,49H,12-14,16-17,19-22H2,1-11H3,(H,47,48);/t23-,24-,25-,26+,27-,28-,29-,30-,31+,32+,33+,34+,36+,37+,38-,40-,41+,42-,43-;/m0./s1

InChI key: InChIKey=FYYNXBXFLJGESK-DAALJYCPSA-N

SMILES: O[C@H]1[C@]2(O[C@@]3(O[C@]([C@H](C([C@H]([C@H]([C@H](C)[C@@]4(O[C@@]([C@H](C(O)=O)CC)([C@@H](C)C[C@@H]4C)[H])[H])O)C)=O)CC)([C@@H](C)C[C@H]3C)[H])C=C1)O[C@@](C)(CC2)[C@@]5(O[C@@H](C)[C@](CC)(O)CC5)[H].[Na]

Synonyms:

• Narasin sodium salt
• 4-Methylsalinomycin sodium
• Salinomycin, 4-methyl-, sodium salt (1:1), (4S)-
• 1,6,8-Trioxadispiro[4.1.5.3]pentadecane, salinomycin deriv.
• Salinomycin, 4-methyl-, monosodium salt, (4S)-
• HainanMycin
• naransin sodium
• Naracin sodium salt
• NARASIN
• Hainan drug
• Narasin sodiuM

Narasin (sodium salt)

CAS: 58331-17-2

Narasin (sodium salt) (HainanMycin) induces tumor necrosis factor-related apoptosis-induced ligand (TRAIL)-mediated apoptosis by ER stress in glioma cells and

Formula: C₄₃H₇₁NaO₁₁

Purity: 98%

Color and Shape: Solid

Molecular weight: 787.01

Ref: TM-T21577

Naransin Sodium

CAS: 58331-17-2

Formula: C₄₃H₇₁O₁₁·Na

Molecular weight: 764.03 22.99

Ref: 4Z-N-109001

Narasin Sodium

Controlled Product

CAS: 58331-17-2

Applications Narasin sodium is an antibacterial and limited antifungal agent.

Formula: C₄₃H₇₁O₁₁·Na

Color and Shape: Neat

Molecular weight: 787.007

Ref: TR-N378773

Narasin sodium

CAS: 58331-17-2

Narasin sodium is an ionophore antibiotic, which is a type of compound that facilitates ion transport across biological membranes. It is derived from the fermentation of the bacterium *Streptomyces aureofaciens*. The mode of action involves the disruption of ion gradients in target organisms, specifically inhibiting the growth of certain pathogenic bacteria and protozoa by altering their cellular ionic balance.

Formula: C₄₃H₇₁NaO₁₁

Purity: Min. 95%

Molecular weight: 787.02 g/mol

Ref: 3D-AN182804