CAS 583840-04-4

2-Carbamoyl-4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)pyridine 1-oxide

CAS: 583840-04-4

2-Carbamoyl-4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)pyridine 1-oxide

Purity: 98%

Molecular weight: 466.8g/mol

Ref: 54-PC1005925

Sorafenib Related Compound 28

CAS: 583840-04-4

Formula: C₂₀H₁₄ClF₃N₄O₄

Color and Shape: Off-White To Grey Solid

Molecular weight: 466.80

Ref: 4Z-S-2749

N-Desmethyl Sorafenib (Pyridine)-N-oxide-d4

Controlled Product

CAS: 583840-04-4

Formula: C₂₀H₁₀D₄ClF₃N₄O₄

Color and Shape: Neat

Molecular weight: 470.82

Ref: TR-D293297

N-Desmethyl Sorafenib (Pyridine)-N-oxide

Controlled Product

CAS: 583840-04-4

Applications N-Desmethyl Sorafenib (Pyridine)-N-oxide is a metabolite of Sorafenib (S676850) and has anti-proliferative activity in human breast cancer cells.
References Tolcher, A.W., et al.: Cancer Chemoth. Pharm., 67, 751 (2011); Cui, P.H., et al.: Biochem. Pharmacol., 86, 419 (2013); Ghassabian, S., et al.: Biochem. Pharmacol., 84, 215 (2012)

Formula: C₂₀H₁₄ClF₃N₄O₄

Color and Shape: Neat

Molecular weight: 466.798

Ref: TR-D293295

N-Desmethyl sorafenib (pyridine)-N-oxide

CAS: 583840-04-4

N-Desmethyl sorafenib (pyridine)-N-oxide is a drug product that can be used as an HPLC standard and is also used in the development of drugs. CAS No. 583840-04-4 is a metabolite impurity that can be found in the analytical API impurity of the drug. This synthetic compound is subject to metabolism studies, which are conducted on animals for pharmacopoeia purposes. N-Desmethyl sorafenib (pyridine)-N-oxide has shown niche applications in the field of research and development, as it can be used as an analytical standard for HPLC.

Formula: C₂₀H₁₄ClF₃N₄O₄

Purity: Min. 95%

Molecular weight: 466.80 g/mol

Ref: 3D-IYA84004

N-Desmethyl Sorafenib (Pyridine)-N-oxide

CAS: 583840-04-4

Formula: C₂₀H₁₄ClF₃N₄O₄

Molecular weight: 466.80

Ref: ST-EA-CP-S16013