CAS 58409-59-9

Bucumolol

Description:

Bucumolol is a chemical compound classified as a beta-adrenergic antagonist, primarily used in the treatment of hypertension and certain cardiovascular conditions. It functions by blocking beta-adrenergic receptors, leading to a decrease in heart rate and blood pressure. Bucumolol exhibits selectivity for beta-1 receptors, which are predominantly found in the heart, making it effective in managing heart-related issues. The compound is typically administered orally and has a moderate duration of action. Its pharmacokinetics involve absorption through the gastrointestinal tract, with metabolism occurring primarily in the liver. Bucumolol may also exhibit some intrinsic sympathomimetic activity, which can influence its overall cardiovascular effects. Common side effects may include fatigue, dizziness, and gastrointestinal disturbances. As with other beta-blockers, caution is advised in patients with asthma or certain types of heart block. Overall, Bucumolol represents a valuable option in the pharmacological management of hypertension and related cardiovascular disorders.

Formula: C₁₇H₂₃NO₄

InChI: InChI=1S/C17H23NO4/c1-11-5-7-14(16-13(11)6-8-15(20)22-16)21-10-12(19)9-18-17(2,3)4/h5-8,12,18-19H,9-10H2,1-4H3

InChI key: InChIKey=CIJVBYRUFLGDHY-UHFFFAOYSA-N

SMILES: O(CC(CNC(C)(C)C)O)C1=C2C(=C(C)C=C1)C=CC(=O)O2

Synonyms:

• (RS)-8-(3-(tert-Butylamino)-2-hydroxyproproxy)-5-methylcoumarin
• 2H-1-Benzopyran-2-one, 8-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-5-methyl-
• 8-(3-((1,1-Dimethylethyl)amino)-2-hydroxypropoxy)-5-methyl-2H-1-benzopyran-2-one
• 8-(3-(tert-Butylamino)-2-hydroxypropoxy)-5-methylcoumarin
• 8-[3-(tert-butylamino)-2-hydroxypropoxy]-5-methyl-2H-chromen-2-one
• Bucumolol [INN]
• Bucumololum
• Bucumololum [INN-Latin]
• Unii-U8Wvj3501L
• dl-Bucumolol
• Bucumolol

Bucumolol

CAS: 58409-59-9

Bucumolol (Bucumarol) is a β-adrenergic blocking agent and a local anesthetic with antihypertensive activity and can be used to study myocardial infarction.

Formula: C₁₇H₂₃NO₄

Purity: 99.66%

Color and Shape: Soild

Molecular weight: 305.37

Ref: TM-T30606L

Bucumolol

CAS: 58409-59-9

Bucumolol

Purity: ≥98%

Molecular weight: 305.37g/mol

Ref: 54-BUP01215

Bucumolol

CAS: 58409-59-9

Formula: C₁₇H₂₃NO₄

Color and Shape: Off-White

Molecular weight: 305.37

Ref: TR-B689395

Bucumolol

CAS: 58409-59-9

Bucumolol is a medicinal compound that has shown promise as an anticancer agent. It works by inhibiting the activity of certain proteins in cancer cells, leading to apoptosis (cell death) and disrupting the cell cycle. Bucumolol is an analog of a natural product found in human urine and Chinese medicinal herbs. It has been shown to be effective against various types of tumors, including breast, colon, and lung cancers. Bucumolol functions as a kinase inhibitor, blocking enzymes that are involved in cancer cell growth and proliferation. Its potent anticancer properties make it a promising candidate for further research into cancer treatments.

Formula: C₁₇H₂₃NO₄

Purity: Min. 95%

Molecular weight: 305.4 g/mol

Ref: 3D-ICA40959