CAS 5843-53-8

(+)-N-(o-chlorobenzyl)-α-methylphenethylamine hydrochloride

Description:

(+)-N-(o-chlorobenzyl)-α-methylphenethylamine hydrochloride, with the CAS number 5843-53-8, is a chemical compound that belongs to the class of substituted phenethylamines. It is characterized by its structural features, which include a phenethylamine backbone with an α-methyl group and an o-chlorobenzyl substituent. This compound is typically encountered as a hydrochloride salt, which enhances its solubility in water and facilitates its handling in laboratory settings. The presence of the o-chlorobenzyl group may influence its pharmacological properties, potentially affecting its interaction with biological targets. As a member of the phenethylamine family, it may exhibit stimulant or psychoactive effects, although specific biological activities can vary widely based on the compound's structure. Safety and handling precautions are essential, as with many organic compounds, due to potential toxicity or regulatory considerations. Overall, this compound is of interest in both synthetic chemistry and pharmacology, warranting further investigation into its properties and applications.

Formula: C₁₆H₁₉Cl₂N

InChI: InChI=1/C16H18ClN.ClH/c1-13(11-14-7-3-2-4-8-14)18-12-15-9-5-6-10-16(15)17;/h2-10,13,18H,11-12H2,1H3;1H

InChI key: InChIKey=ASTCUURTJCZRSC-UHFFFAOYNA-N

SMILES: CC(Cc1ccccc1)NCc1ccccc1Cl.Cl

Synonyms:

• (+)-N-(o-Chlorobenzyl)-alpha-methylphenethylamine hydrochloride
• Asenlix
• Ba 7205
• Benzeneethanamine, N-[(2-chlorophenyl)methyl]-α-methyl-, hydrochloride (1:1), (+)-
• Benzeneethanamine, N-[(2-chlorophenyl)methyl]-α-methyl-, hydrochloride, (+)-
• Chlorhydrate de d-N-(phenyl-1 propyl-2) chloro-2 benzylamine
• Chlorhydrate de d-N-(phenyl-1 propyl-2) chloro-2 benzylamine [French]
• Clobenzorex HCl
• Clobenzorex hydrochloride
• Dinintel
• N-(2-chlorobenzyl)-1-phenylpropan-2-amine hydrochloride (1:1)
• Phenethylamine, N-(o-chlorobenzyl)-alpha-methyl-, hydrochloride, (+)-
• Phenethylamine, N-(o-chlorobenzyl)-α-methyl-, hydrochloride, (+)-
• Rexigen

Clobenzorex Hydrochloride

Controlled Product

CAS: 5843-53-8

Color and Shape: Neat

Ref: 61-FOR0649.00

Clobenzorex Hydrochloride 1.0 mg/ml in Methanol (as free base)

Controlled Product

CAS: 5843-53-8

Color and Shape: Single Solution

Ref: 61-AMP0649.00-01

Clobenzorex Hydrochloride

Controlled Product

CAS: 5843-53-8

Color and Shape: Neat

Ref: 86-MM0649.00

(S)-(+)-Clobenzorex Hydrochloride

Controlled Product

CAS: 5843-53-8

Applications The S-enantiomer of Clobenzorex (C583000), an anorexic.
References Thomasset, M., et al.: Experienta, 26, 692 (1970), Glasson, B., et al.: Arzneim.-Forsch., 21, 1985 (1971),

Formula: C₁₆H₁₈ClN·ClH

Color and Shape: Neat

Molecular weight: 296.23

Ref: TR-C582990

N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride

Controlled Product

CAS: 5843-53-8

N-(2-Chlorobenzyl)-1-phenylpropan-2-amine hydrochloride (CBP) is a potent stimulant drug that is used to treat chronic pain. It has been shown to be effective in the treatment of alopecia areata and inflammatory diseases, such as Crohn's disease, ulcerative colitis, and rheumatoid arthritis. CBP blocks protein synthesis by inhibiting the activity of the enzyme dinucleotide phosphate (DNP). This inhibition leads to the accumulation of adenosine monophosphate (AMP), which inhibits cyclic AMP production and protein synthesis. CBP also prevents the binding of DNP to RNA polymerase II at promoter sites, leading to a decrease in mRNA production. As a result, CBP may inhibit protein synthesis by preventing transcription or translation.

Formula: C₁₆H₁₈ClN•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 296.24 g/mol

Ref: 3D-FC131572

(S)-(+)-Clobenzorex Hydrochloride (1 mg/mL in Acetonitrile)

Controlled Product

CAS: 5843-53-8

Formula: C₁₆H₁₈ClN·ClH

Color and Shape: Single Solution

Molecular weight: 296.23

Ref: TR-KIT3735