CAS 5845-66-9

3-(4-hydroxybenzyl)piperazine-2,5-dione

Description:

3-(4-Hydroxybenzyl)piperazine-2,5-dione, with the CAS number 5845-66-9, is a chemical compound that belongs to the class of piperazine derivatives. This substance features a piperazine ring, which is a six-membered cyclic amine, substituted with a 4-hydroxybenzyl group and two carbonyl groups at the 2 and 5 positions of the ring, giving it a diketone structure. The presence of the hydroxyl group contributes to its potential as a phenolic compound, which may exhibit various biological activities. The compound is typically characterized by its solid state at room temperature and may be soluble in polar organic solvents. Its molecular structure suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals, due to the piperazine moiety's known role in drug design. Additionally, the compound's functional groups may allow for further chemical modifications, enhancing its utility in various chemical reactions or as a precursor in synthetic pathways.

Formula: C₁₁H₁₂N₂O₃

InChI: InChI=1/C11H12N2O3/c14-8-3-1-7(2-4-8)5-9-11(16)12-6-10(15)13-9/h1-4,9,14H,5-6H2,(H,12,16)(H,13,15)

SMILES: c1cc(ccc1CC1C(=NCC(=N1)O)O)O

Synonyms:

• Cyclic (glycyl-L-tyrosine)
• 3-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione
• (S)-3-(4-hydroxybenzyl)piperazine-2,5-dione
• Tryptophan Impurity 37
• 3-((4-Hydroxyphenyl)methyl)-2,5-piperazinedione
• 2,5-Piperazinedione, 3-[(4-hydroxyphenyl)methyl]-, (3S)-
• Cyclic(glycyl-L-tyrosyl)
• Cyclo(-Gln-Tyr)
• Levothyroxine Related Compound 1 (N-Acetyl-3,5-Diiodo-L-Tyrosine)
• 3-(S)-(4-Hydroxybenzyl)piperazine-2,5-dione
• 3-(4-hydroxybenzyl)piperazine-2,5-dione
• Cyclo(L-tyrosylglycine)

Cyclo(Gly-Tyr)

CAS: 5845-66-9

Formula: C₁₁H₁₂N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 220.2246

Ref: IN-DA003AC3

Cyclo(Gly-Tyr)

CAS: 5845-66-9

Cyclo(Gly-Tyr)

Purity: ≥98%

Molecular weight: 220.22g/mol

Ref: 54-BUP20925

Cyclo(Gly-Tyr)

CAS: 5845-66-9

Cyclo(Gly-Tyr) is a cyclic dipeptide formed from glycine and tyrosine linked head-to-tail by peptide bonds, which has unique biological properties.

Formula: C₁₁H₁₂N₂O₃

Purity: 99.07%

Color and Shape: Solid

Molecular weight: 220.22

Ref: TM-T40666

Cyclic(glycyl-L-tyrosyl)

CAS: 5845-66-9

Cyclic(glycyl-L-tyrosyl) is a phenolic compound and the main metabolite of the dietary supplement resveratrol. It has been shown to have interactions with cellular transport, as well as the ability to activate a number of proteins that are involved in cellular transport. Cyclic(glycyl-L-tyrosyl) also interacts with hydroxyl groups on proteins and activates them, which may lead to the uptake of these proteins by cells. This interaction between cyclic(glycyl-L-tyrosyl) and hydroxyl groups on proteins may be due to its conformation and affinity for this residue. Cyclic(glycyl-L-tyrosyl) has been reported to inhibit the binding of glucosamine to NUDIX hydrolase, as well as preventing glucosamine from activating NUDIX hydrolase.

Formula: C₁₁H₁₂N₂O₃

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 220.22 g/mol

Ref: 3D-FC46820

Cyclo(Gly-Tyr)

CAS: 5845-66-9

Purity: 98%

Molecular weight: 220.085

Ref: 10-F862528

Cyclo(-Gly-Tyr)

Controlled Product

CAS: 5845-66-9

Applications Cyclo(-Gly-Tyr) is used to prepare aryl-fused benzodiazepine D2 receptor antagonists as antipsychotics.
References Aicher, T., et al.: PCT Int. Appl., WO 2003082877 A1 20031009 (2003)

Formula: C₁₁H₁₂N₂O₃

Color and Shape: Neat

Molecular weight: 220.22

Ref: TR-C987420