CAS 5845-67-0

Cyclo(glycyl-L-leucyl)

Description:

Cyclo(glycyl-L-leucyl) is a cyclic dipeptide composed of two amino acids: glycine and leucine. Its structure features a cyclic arrangement, which can influence its biological activity and stability compared to linear peptides. The presence of the leucine residue contributes to hydrophobic characteristics, while glycine, being the simplest amino acid, provides flexibility in the peptide chain. This compound is known for its potential roles in various biological processes, including acting as a signaling molecule or influencing protein folding. Cyclo(glycyl-L-leucyl) may exhibit unique pharmacological properties, making it of interest in medicinal chemistry and drug development. Its CAS number, 5845-67-0, is a unique identifier that facilitates the search for information regarding its properties, synthesis, and applications. Overall, the cyclic nature and specific amino acid composition of cyclo(glycyl-L-leucyl) contribute to its distinct chemical behavior and potential utility in biochemical research and therapeutic contexts.

Formula: C₈H₁₄N₂O₂

InChI: InChI=1S/C8H14N2O2/c1-5(2)3-6-8(12)9-4-7(11)10-6/h5-6H,3-4H2,1-2H3,(H,9,12)(H,10,11)/t6-/m0/s1

InChI key: InChIKey=VQFHWKRNHGHZTK-LURJTMIESA-N

SMILES: C(C(C)C)[C@H]1C(=O)NCC(=O)N1

Synonyms:

• (3S)-3-(2-Methylpropyl)-2,5-piperazinedione
• (3S)-3-(2-methylpropyl)piperazine-2,5-dione
• (S)-3-Isobutylpiperazine-2,5-dione
• 2,5-Piperazinedione, 3-(2-methylpropyl)-, (3S)-
• 2,5-Piperazinedione, 3-(2-methylpropyl)-, (S)-
• 2,5-Piperazinedione, 3-isobutyl-, <span class="text-smallcaps">L</span>-
• 3-(2-Methylpropyl)Piperazine-2,5-Dione
• <span class="text-smallcaps">L</span>-Leucylglycine diketopiperazine
• Cyclo(<span class="text-smallcaps">L</span>-leucylglycine)
• Cyclo(<span class="text-smallcaps">L</span>-leucylglycyl)
• Cyclo(glycyl-<span class="text-smallcaps">L</span>-leucyl)
• Cyclo-(Gly-Leu)
• Cyclo(glycyl-L-leucyl)
• Cyclo(-Leu-Gly)

Cyclo(-Gly-Leu)

CAS: 5845-67-0

Formally derived from the C-terminal dipeptide of oxytocin., cyclo(Leu-Gly) is active in memory processes. The diketopiperazine blocks the narcotic-induced dopamine receptor supersensitivity.

Formula: C₈H₁₄N₂O₂

Purity: > 99%

Color and Shape: White Lyophilisate

Molecular weight: 170.21

Ref: 01-4004738

CYCLO(-LEU-GLY)

CAS: 5845-67-0

Formula: C₈H₁₄N₂O₂

Purity: %

Color and Shape: Solid

Molecular weight: 170.2090

Ref: IN-DA00E9WI

Cyclo(glycyl-L-leucyl)

CAS: 5845-67-0

Cyclo(glycyl-L-leucyl)

Purity: 95%

Molecular weight: 170.21g/mol

Ref: 54-OR1006364

Cyclo(Leu-Gly)

Controlled Product

CAS: 5845-67-0

Applications Cyclo(Leu-Gly) is an antimicrobial compound produced by Latobacillus plantarum.
References Niku-Paavola, M., et al.: J. Appl. Microbiol., 86, 29 (1999)

Formula: C₈H₁₄N₂O₂

Color and Shape: Off-White

Molecular weight: 170.21

Ref: TR-C984485

(S)-3-Isobutylpiperazine-2,5-dione

CAS: 5845-67-0

Formula: C₈H₁₄N₂O₂

Purity: 95+%

Molecular weight: 170.212

Ref: 10-F463126

Morphine Tolerance Peptide

CAS: 5845-67-0

Morphine tolerance peptide is a cyclic peptide analog of morphine. It has been shown to have an affinity for the kappa-opioid receptor that is similar to that of morphine, but it has a higher potency and a longer duration of action. The molecular modeling study indicates that the analog interacts with the receptor in a similar manner as morphine and exhibits high selectivity for this receptor. The analog also shares many of the same features as morphine in terms of depressant effect and locomotor activity, but does not produce any kind of withdrawal syndrome.

Formula: C₈H₁₄N₂O₂

Purity: Min. 95%

Molecular weight: 170.21 g/mol

Ref: 3D-PMT-4070