CAS 58510-66-0

Uridine, 2',5'-dideoxy-5'-iodo-

Description:

Uridine, 2',5'-dideoxy-5'-iodo- (CAS 58510-66-0) is a modified nucleoside that features a uracil base linked to a ribose sugar, which has been chemically altered to include a 5-iodo substitution and lacks the hydroxyl group at the 2' and 5' positions of the sugar. This modification can influence its biological activity and stability compared to standard uridine. The presence of iodine may enhance its potential for use in various biochemical applications, including as a probe in nucleic acid research or in the development of antiviral agents. The absence of hydroxyl groups at the 2' and 5' positions can also affect its interactions with enzymes and its incorporation into RNA. As a nucleoside analog, it may exhibit unique pharmacological properties, making it of interest in medicinal chemistry and molecular biology. Its solubility, reactivity, and interaction with biological systems would be influenced by these structural modifications, which can be critical for its function in research and therapeutic contexts.

Formula: C₉H₁₁IN₂O₄

2',5'-Dideoxy-5'-iodouridine

CAS: 58510-66-0

2',5'-Dideoxy-5'-iodouridine is a Nucleoside Derivative - 5'-Modified nucleoside, Halo-nucleoside.

Formula: C₉H₁₁IN₂O₄

Color and Shape: Solid

Molecular weight: 338.1

Ref: TM-TNU1150

2’,5’-Dideoxy-5’-iodouridine

CAS: 58510-66-0

2’,5’-Dideoxy-5’-iodouridine is an antiviral drug that inhibits DNA synthesis. It is a modified nucleoside analog with a phosphoramidite derivative of the natural ribonucleosides and deoxyribonucleosides. This drug is synthesized through the reaction of 2’,5’-dideoxyadenosine with 5-iodo-2-deoxyuridine in the presence of a strong base such as sodium hydride. The resulting product has a high purity, high yield, and can be used for the synthesis of DNA. 2’,5’-Dideoxy-5’-iodouridine also has anticancer properties and has been shown to inhibit cell growth in vitro at concentrations ranging from 0.1 to 1 μM.

Purity: Min. 95%

Ref: 3D-ND163032