CAS 5854-93-3

L-Alanosine

Description:

L-Alanosine, with the CAS number 5854-93-3, is an amino acid derivative that is primarily recognized for its role in biochemical research and potential therapeutic applications. It is characterized by its structural similarity to other amino acids, featuring an amino group, a carboxyl group, and a side chain that distinguishes it from other members of the amino acid family. L-Alanosine is known to participate in various metabolic pathways and can influence cellular processes due to its involvement in protein synthesis and enzyme activity. Its solubility in water and stability under physiological conditions make it suitable for laboratory studies. Additionally, L-Alanosine has garnered interest for its potential effects on neurotransmitter systems and its implications in neuropharmacology. As with many amino acids, its properties can be influenced by pH and temperature, which are critical factors to consider in experimental settings. Overall, L-Alanosine serves as a valuable compound in both research and potential clinical applications.

Formula: C₃H₇N₃O₄

InChI: InChI=1S/C3H7N3O4/c4-2(3(7)8)1-6(10)5-9/h2,10H,1,4H2,(H,7,8)/t2-/m0/s1

InChI key: InChIKey=MLFKVJCWGUZWNV-REOHCLBHSA-N

SMILES: C([C@@H](C(O)=O)N)N(N=O)O

Synonyms:

• (-)-(S)-2-Amino-3-(hydroxynitrosamino)propionic acid
• (-)-(S)-2-Amino-3-(hydroxynitrosamino)propionsaeure
• (2S)-2-Amino-3-[hydroxy(nitroso)amino]propanoic acid
• (S)-2-Amino-3-(hydroxy(nitroso)amino)propanoic acid
• 2-Amino-3-(hydroxynitrosamino)propionic acid, L-
• 3-(Hydroxynitrosoamino)-<span class="text-smallcaps">L</span>-alanine
• 3-(Hydroxynitrosoamino)-L-alanine
• <span class="text-smallcaps">L</span>-2-Amino-3-(N-nitroso)hydroxylaminopropionic acid
• <span class="text-smallcaps">L</span>-2-Amino-3-(hydroxynitrosamino)propionic acid
• <span class="text-smallcaps">L</span>-Alanine, 3-(hydroxynitrosoamino)-
• <span class="text-smallcaps">L</span>-Alanosine
• Ai3-52867
• Alanosina
• Alanosina [Spanish]
• Alanosine (L)
• Alanosine (VAN)
• Alanosine [INN]
• Alanosinum
• Alanosinum [Latin]
• Brn 2046850
• L-2-Amino-3-((N-nitroso)hydroxylamino)propionic acid
• L-2-Amino-3-(N-nitroso)hydroxylaminopropionic acid
• L-2-Amino-3-(hydroxynitrosamino)propionic acid
• L-Alanine, 3-(hydroxynitrosoamino)- (9CI)
• L-Alanosine
• NSC 529469
• Nsc 153353
• Propionic acid, 2-amino-3-(hydroxynitrosamino)-, (L)-
• Propionic acid, 2-amino-3-(hydroxynitrosamino)-, <span class="text-smallcaps">L</span>-
• Sdx 102
• Unii-2Cni71214Y
• L-Alanine, 3-(hydroxynitrosoamino)-

L-Alanosine

CAS: 5854-93-3

L-Alanosine

Purity: ≥95%

Molecular weight: 149.11g/mol

Ref: 54-BUP21721

L-Alanosine

CAS: 5854-93-3

Molecular weight: 149.11

Ref: 7W-GM7931

L-Alanosine

CAS: 5854-93-3

L-Alanosine, an antibioticfrom tStreptomyces alanosinicus, inhibits tumor cell proliferation by blocking the adenylosuccinate synthetic pathway.

Formula: C₃H₇N₃O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 149.11

Ref: TM-T15691

L-Alanosine

CAS: 5854-93-3

Formula: C₃H₇N₃O₄

Molecular weight: 149.11

Ref: 4Z-A-390001

L-Alanosine

CAS: 5854-93-3

L-Alanosine is a nucleotide that is synthesized from adenosine and alanine. It is the first substrate in the synthetic pathway of l-alanosine. L-Alanosine has been shown to have antibiotic properties against gram negative bacteria, such as Escherichia coli and Klebsiella pneumoniae. L-Alanosine inhibits synthesis of bacterial cell walls by interfering with the enzymatic activity of bacterial ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. The molecule also inhibits protein synthesis by binding to the 30S subunit of bacterial ribosomes, preventing elongation of polypeptide chains. In vivo treatment with L-alanosine significantly reduced tumor size and increased levels of ATP in colorectal adenocarcinoma cells.
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Formula: C₃H₇N₃O₄

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 149.11 g/mol

Ref: 3D-FA17253

L-Alanosine

Controlled Product

CAS: 5854-93-3

Applications L-Alanosine is an antitumor antibiotic substance from the fermentation of Streptomyces alanosinicus. It is the first natural product found to have a N-nitrosohydroxylamino group on an aliphatic chain. It is also an experimental insect reproduction inhibitor.
References Murthy, et al.: Nature, 211 1198 (1966); Thiemann, B., et al.: J. Antibiot., 19A, 155 (1966); Gale, et al.: Biochem, Pharmacol., 17, 363 (1968); Kenaga, E.E., et al.: J. Econ. Entomol., 62, 1006 (1969); Matsumoto, S., et al.: Agric. Biol. Chem., 48, 827 (1984); Weick, J., et al.: Invest. New Drugs, 3, 249 (1983)

Formula: C₃H₇N₃O₄

Color and Shape: Neat

Molecular weight: 149.11

Ref: TR-A510810

L-Alanosine

CAS: 5854-93-3

Formula: C₃H₇N₃O₄

Molecular weight: 149.11

Ref: ST-EA-CP-A325001