CAS 58546-54-6

Gomisin A

Description:

Gomisin A is a natural compound classified as a lignan, primarily derived from the fruit of the Schisandra chinensis plant, commonly known for its traditional medicinal uses. It is characterized by its complex polycyclic structure, which contributes to its biological activity. Gomisin A exhibits various pharmacological properties, including antioxidant, anti-inflammatory, and hepatoprotective effects, making it of interest in both traditional medicine and modern pharmacology. The compound has been studied for its potential neuroprotective effects and its ability to modulate certain signaling pathways, which may have implications for conditions such as neurodegenerative diseases. Additionally, Gomisin A has shown promise in enhancing liver function and protecting against liver damage. Its solubility and stability in different solvents can vary, influencing its bioavailability and efficacy in therapeutic applications. Overall, Gomisin A represents a significant area of research in natural products chemistry and pharmacology, highlighting the importance of plant-derived compounds in health and disease management.

Formula: C₂₃H₂₈O₇

InChI: InChI=1S/C23H28O7/c1-12-7-13-8-16-20(30-11-29-16)22(28-6)17(13)18-14(10-23(12,2)24)9-15(25-3)19(26-4)21(18)27-5/h8-9,12,24H,7,10-11H2,1-6H3

InChI key: InChIKey=ZWRRJEICIPUPHZ-UHFFFAOYSA-N

SMILES: O(C)C1=C2C=3C(=CC(OC)=C(OC)C3OC)CC(C)(O)C(C)CC2=CC4=C1OCO4

Synonyms:

• (6R,7R)-1,2,3,13-Tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol
• (6S,7S)-1,2,3,13-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol
• (6S,7S,13aR)-5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-6-ol
• 1,2,3,13-Tetramethoxy-6,7-Dimethyl-5,6,7,8-Tetrahydrobenzo[3',4']Cycloocta[1',2':4,5]Benzo[1,2-D][1,3]Dioxol-6-Ol
• Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-6-ol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, (6S,7S,13aR)-
• Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-6-ol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, stereoisomer
• Gomisin A
• Schisandrol B
• Schisantherinol B
• Tjn 101
• Wuweizi alcohol B
• Wuweizichun B
• benzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, (6R,7R)-

Gomisin A

CAS: 58546-54-6

Formula: C₂₃H₂₈O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 416.4642

Ref: IN-DA003U7V

Schisandrol B

CAS: 58546-54-6

Schisandrol B

Purity: ≥98%

Molecular weight: 416.46g/mol

Ref: 54-BUP10550

Schizandrol B

CAS: 58546-54-6

Schizandrol B

Purity: 99%

Molecular weight: 416.46g/mol

Ref: 54-OR1023901

Schisandrol B

CAS: 58546-54-6

Formula: C₂₃H₂₈O₇

Molecular weight: 416.46

Ref: 7W-GP1275

Schizandrol B

CAS: 58546-54-6

Gomisin A has anti-inflammatory, antihypertensive, neuroprotective, and anti-proliferation properties, it induces marked protective effects against hepatic and renal injury induced by CCl(4) exposure through differential regulation of the MAPK signal transduction pathway. Gomisin A inhibits COX-2, iNOS, IL-6, TNF-α and NO through the down-regulation of RIP2 and NF-κB activation.

Formula: C₂₃H₂₈O₇

Purity: 95%~99%

Molecular weight: 416.47

Ref: BP-BP1266

Gomisin A

CAS: 58546-54-6

Formula: C₂₃H₂₈O₇

Purity: >96.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 416.47

Ref: 3B-G0537

Schisandrol B

CAS: 58546-54-6

Schisandrol B fights neuroinflammation, liver/renal damage, and reduces cell growth via multiple signaling pathways.

Formula: C₂₃H₂₈O₇

Purity: 99.14% - 99.95%

Color and Shape: Solid

Molecular weight: 416.46

Ref: TM-T6S1917

Schisandrol b

CAS: 58546-54-6

Ether alcohol phenol

Formula: C₂₃H₂₈O₇

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 416.47

Ref: 5G-80206

Schizandrol B

Controlled Product

CAS: 58546-54-6

Schizandrol B is a natural compound that has been shown to protect against oxidative stress and decrease the mitochondrial membrane potential. Schizandrol B inhibits human cyp3a4, which is an enzyme that metabolizes drugs. The linear calibration curve was able to be obtained from the signal pathways in human cells. The analytical method used was matrix effect-free. Experimental models were used to show that schizandrol B has an inhibitory effect on locomotor activity and skin tumor formation. It also has been found to be a substrate for p-gp, which transports drugs across the cell membrane, and can therefore alter absorption of drugs, including gomisin A. Schizandrol B also modulates enzyme activities in vitro as well as in vivo.

Formula: C₂₃H₂₈O₇

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 416.46 g/mol

Ref: 3D-FS65449

Schizandrol B - Bio-X ™

Controlled Product

CAS: 58546-54-6

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₂₃H₂₈O₇

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 416.46 g/mol

Ref: 3D-BS300127