CAS 58546-56-8

Schisantherin A

Description:

Schisantherin A is a natural compound classified as a lignan, primarily derived from the plant species Schisandra chinensis, which is known for its medicinal properties. This compound exhibits a complex molecular structure characterized by multiple aromatic rings and hydroxyl groups, contributing to its biological activity. Schisantherin A is recognized for its antioxidant properties, which help in scavenging free radicals and reducing oxidative stress. Additionally, it has been studied for its potential neuroprotective effects, anti-inflammatory activities, and ability to modulate various signaling pathways in cells. The compound's pharmacological profile suggests potential applications in traditional medicine, particularly in enhancing liver function and promoting overall health. Its solubility and stability in various solvents make it suitable for further research and development in the fields of pharmacology and natural product chemistry. As with many natural compounds, ongoing studies are essential to fully elucidate its mechanisms of action and therapeutic potential.

Formula: C₃₀H₃₂O₉

InChI: InChI=1S/C30H32O9/c1-16-12-18-13-21-25(38-15-37-21)26(35-5)22(18)23-19(14-20(33-3)24(34-4)27(23)36-6)28(30(16,2)32)39-29(31)17-10-8-7-9-11-17/h7-11,13-14,16,28,32H,12,15H2,1-6H3

InChI key: InChIKey=UFCGDBKFOKKVAC-UHFFFAOYSA-N

SMILES: O(C)C1=C2C=3C(=CC4=C(C3OC)OCO4)CC(C)C(C)(O)C(OC(=O)C5=CC=CC=C5)C2=CC(OC)=C1OC

Synonyms:

• (5R,6S,7S)-6-hydroxy-1,2,3,13-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-5-yl benzoate
• (5S,6S,7S)-6-hydroxy-1,2,3,13-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-5-yl benzoate
• (5S-(5alpha,6beta,7beta))-5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethylbenzo(3,4)cycloocta(1,2-f)(1,3)benzodioxole-5,6-diol 5-benzoate
• 6-Hydroxy-1,2,3,13-Tetramethoxy-6,7-Dimethyl-5,6,7,8-Tetrahydrobenzo[3',4']Cycloocta[1',2':4,5]Benzo[1,2-D][1,3]Dioxol-5-Yl Benzoate
• Benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxole-5,6-diol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, 5-benzoate, (5S-(5alpha,6beta,7beta))-
• Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxole-5,6-diol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, 5-benzoate, (5S,6S,7S,13aS)-
• Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxole-5,6-diol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, 5-benzoate, stereoisomer
• Gomisin C
• Schizantherin A
• Wuweizi ester A
• Schisantherin A

Schisantherin A

CAS: 58546-56-8

Formula: C₃₀H₃₂O₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 536.5697

Ref: IN-DA00E96C

Schizantherin A

CAS: 58546-56-8

Formula: C₃₀H₃₂O₉

Molecular weight: 536.58

Ref: 7W-GY0185

Schisantherin A

CAS: 58546-56-8

Schisantherin A

Purity: ≥98%

Molecular weight: 536.57g/mol

Ref: 54-BUP00173

Schisantherin A

CAS: 58546-56-8

Schisantherin A

Purity: 98%

Molecular weight: 536.57g/mol

Ref: 54-OR1025610

Gomisin C

CAS: 58546-56-8

Formula: C₃₀H₃₂O₉

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 536.58

Ref: 3B-G0538

Schizantherin A

CAS: 58546-56-8

Schisantherin A exhibits anti-tussive, sedative, anti-inflammatory, antioxidant, anti-osteoporotic, neuroprotective, cognition enhancing, and cardioprotective activities. Schisantherin A can significantly attenuate Aβ1-42-induced learning and memory impairment and noticeably improve the histopathological changes in the hippocampus. Schisantherin A exhibits neuroprotection against 1-methyl-4-phenylpyridinium ion (MPP(+)) through the regulation of two distinct pathways including increasing CREB-mediated Bcl-2 expression and activating PI3K/Akt survival signaling.

Formula: C₃₀H₃₂O₉

Purity: 95%~99%

Molecular weight: 536.577

Ref: BP-BP1267

Schisantherin A

CAS: 58546-56-8

Schisantherin A, a lignan from Schisandra fruit, is used as an antitussive, tonic, and sedative.

Formula: C₃₀H₃₂O₉

Purity: 98% - 99.989

Color and Shape: Solid

Molecular weight: 536.57

Ref: TM-T2913

Schisantherin a

CAS: 58546-56-8

Carboxylic acid with additional oxygen functions

Formula: C₃₀H₃₂O₉

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 536.58

Ref: 5G-89316

Gomisin C

Controlled Product

CAS: 58546-56-8

Gomisin C is a natural compound that has been shown to have antioxidant and anti-inflammatory effects. It has been shown to inhibit the mitochondrial membrane potential, which leads to cytosolic Ca2+ accumulation. Gomisin C also inhibits 3T3-L1 preadipocyte differentiation. This compound also inhibits the polymerase chain reaction of DNA in cells, as well as the formation of crystalline cellulose and fructus. Gomisin C has been shown to be effective against neuronal death induced by ischemia–reperfusion injury and skin tumor formation induced by chemical carcinogens. It also inhibits drug transporter activity, voltage-dependent calcium channels, and enzyme activities.

Formula: C₃₀H₃₂O₉

Purity: 80%

Color and Shape: White Powder

Molecular weight: 536.57 g/mol

Ref: 3D-FG09971

Schisantherin A

Controlled Product

CAS: 58546-56-8

Applications Schisantherin A is a ligand from Schisandra chinensis. It is capable of suppressing interleukin-1β-induced inflammation in human chondrocytes by inhibiting NF-κB and MAPKs activation.
References ?Liao, S. et al.: Eur. J. Pharmacol 780, 65 (2016); Liu, H., et al.: J Funct Foods 19, 296 (2015)

Formula: C₃₀H₃₂O₉

Color and Shape: Neat

Molecular weight: 536.57

Ref: TR-S199100