CAS 58551-69-2

Carboprost tromethamine

Description:

Carboprost tromethamine, with the CAS number 58551-69-2, is a synthetic prostaglandin analog primarily used in medical applications, particularly in obstetrics and gynecology. It is a white to off-white crystalline powder that is soluble in water and exhibits a pH range typically between 5.0 and 7.0 when dissolved. This compound is known for its ability to induce uterine contractions, making it effective in managing postpartum hemorrhage and in medical abortion protocols. Carboprost tromethamine acts by stimulating the myometrium, leading to increased uterine tone and contractions. Additionally, it can cause side effects such as gastrointestinal disturbances, fever, and flushing. Due to its potent biological activity, it is administered under strict medical supervision, often via injection. The stability of Carboprost tromethamine is influenced by factors such as temperature and light, necessitating proper storage conditions to maintain its efficacy. Overall, its unique properties and mechanisms of action make it a valuable agent in reproductive health care.

Formula: C₂₁H₃₆O₅·C₄H₁₁NO₃

InChI: InChI=1S/C21H36O5.C4H11NO3/c1-3-4-9-13-21(2,26)14-12-17-16(18(22)15-19(17)23)10-7-5-6-8-11-20(24)25;5-4(1-6,2-7)3-8/h5,7,12,14,16-19,22-23,26H,3-4,6,8-11,13,15H2,1-2H3,(H,24,25);6-8H,1-3,5H2/b7-5-,14-12+;/t16-,17-,18+,19-,21+;/m1./s1

InChI key: InChIKey=UMMADZJLZAPZAW-XOWPVRJPSA-N

SMILES: C(/C=C\CCCC(O)=O)[C@@H]1[C@@H](/C=C/[C@@](CCCCC)(C)O)[C@H](O)C[C@@H]1O.C(CO)(CO)(CO)N

Synonyms:

• (5E,8beta,9beta,11beta,12xi,13Z,15S)-9,11,15-trihydroxy-15-methylprosta-5,13-dien-1-oic acid-2-amino-2-(hydroxymethyl)propane-1,3-diol (1:1)
• (5E,9alpha,11alpha,13E,15S)-9,11,15-trihydroxy-15-methylprosta-5,13-dien-1-oic acid
• (5Z,9-Alpha,11-Alpha,13E,15S)-9,11,15-Trihydroxy-15-Methylprosta-5,13-Dien-1
• (5Z,9alpha,11alpha,13E,15S)-9,11,15-trihydroxy-15-methylprosta-5,13-dien-1-oic acid
• (5Z,9alpha,11alpha,13E,15S)-9,11,15-trihydroxy-15-methylprosta-5,13-dien-1-oic acid-2-amino-2-(hydroxymethyl)propane-1,3-diol (1:1)
• 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, (5Z,9α,11α,13E,15S)-9,11,15-trihydroxy-15-methylprosta-5,13-dien-1-oate (salt)
• Carboprost Tromethamine(5Z,9α,11α,12ξ,13E,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oic acid
• Carboprost trometamol
• Carboprost tromethamine Salt
• Hemabate
• Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-15-methyl-, (5Z,9α,11α,13E,15S)-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
• Prostin 15M
• Prostinfenem
• Prostodin
• U 32921E

CARBOPROST FOR SYSTEM SUITABILITY CRS

CAS: 58551-69-2

CARBOPROST FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0002529

CARBOPROST TROMETAMOL CRS

CAS: 58551-69-2

CARBOPROST TROMETAMOL CRS

Formula: C₂₅H₄₇NO₈

Color and Shape: Added

Molecular weight: 489.6426

Ref: 41-Y0000475

Carboprost Tromethamine

CAS: 58551-69-2

Prostaglandins, thromboxanes and leukotrienes, their derivatives and structural analogues

Formula: C₂₁H₃₆O₅·C₄H₁₁NO₃

Color and Shape: White Off-White Powder

Molecular weight: 368.25627

Ref: 45-1096509

Carboprost tromethamine

CAS: 58551-69-2

Carboprost tromethamine, a synthetic 15-methyl analogue of prostaglandin F2α, effectively promotes uterine contractions and significantly reduces bleeding

Formula: C₂₅H₄₇NO₈

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 489.64

Ref: TM-T14865

Carboprost tromethamine

CAS: 58551-69-2

Formula: C₂₅H₄₅NO₇

Purity: 97%

Color and Shape: Solid

Molecular weight: 471.6273

Ref: IN-DA00E92Q

Carboprost Trometamol

CAS: 58551-69-2

Formula: C₂₁H₃₆O₅·C₄H₁₁NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 368.52 121.14

Ref: 4Z-C-172001

Carboprost tromethamine

CAS: 58551-69-2

Carboprost tromethamine

Purity: ≥98%

Molecular weight: 489.64g/mol

Ref: 54-BUP14618

Carboprost Tromethamine

CAS: 58551-69-2

Carboprost Tromethamine

Purity: 95%

Molecular weight: 489.64g/mol

Ref: 54-OR1024078

Carboprost Tromethamine

Controlled Product

CAS: 58551-69-2

Stability Hygroscopic
Applications Carboprost Tromethanimine is the salt of Carboprost (C177580), an analog of prostaglandin F2α.
References Weeks, J.R., et al.: J. Pharmacol. Exp. Ther., 67, 186 (1973), Csapo, A.I., et al.: Prostaglandins, 18, 479 (1979), Schwallie, P.C., et al.: J. Reprod. Med., 23, 289 (1979), Mapa, M.P., et al.: Int. J. Gynaecol. Obstet., 20, 125 (1982),

Formula: C₂₁H₃₆O₅·C₄H₁₁NO₃

Color and Shape: Neat

Molecular weight: 489.64

Ref: TR-C177600

Carboprost tromethamine

CAS: 58551-69-2

Carboprost tromethamine is a synthetic prostaglandin analogue that is used to induce labor in pregnant women. Carboprost tromethamine has minimal toxicity and can be combined with other drugs to improve efficacy. This drug has been shown to be effective in combination therapy groups, with minimal side effects. Carboprost tromethamine inhibits the activity of the enzyme phospholipase A2, which is responsible for the breakdown of fatty acids and production of inflammatory mediators. It also has anti-inflammatory properties and can be used as a treatment for metabolic disorders such as bladder dysfunction. Carboprost tromethamine is not active against bacteria or fungi, but it does have some antibacterial properties that may come from its ability to inhibit bacterial rRNA synthesis at high concentrations. Carboprost tromethamine should not be used during pregnancy or breastfeeding due to its potential risk of uterine contractions after childbirth, which can interfere with placental

Formula: C₂₅H₄₇NO₈

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 489.64 g/mol

Ref: 3D-FC34897

CARBOPROST TROMETAMOL FOR ASSAY CRS

CAS: 58551-69-2

CARBOPROST TROMETAMOL FOR ASSAY CRS

Ref: 41-Y0002528